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Upregulation of sphingosine kinase 1 (SPHK1) protein has been reported to be associated with a poor prognosis in a variety of malignant tumors. However, the role of SPHK1 in bladder cancer (BC) has not been thoroughly elucidated. The purpose of this study was to assess SPHK1 expression and to explore its contribution to BC. Real-time quantitative reverse(More)
This study further investigates the influence of temporarily disrupting the blood-brain barrier (BBB) on the level of manganese used in AIM fMRI other than the recognized function of allowing that substance to enter into the activated brain regions more effectively during the BBB opening. We injected manganese into Wistar rats through ICA following the(More)
Fault-tolerant scheduling is an important issue for optimal heterogeneous distributed systems because of a wide range of resource failures. Primary-backup approach is a common methodology used for fault tolerance wherein each task has a primary copy and a backup copy on two different processors. For independent tasks, the backup copy can overload with other(More)
In bioinformatics,proteins are coded by strings, called “primary structures”. Biologists have long enough gathered these primary structures in large databases. Numerous experiments and analyses of primary structures have revealed that the protein primary structure closely correlates with the protein second structure. In this paper, we present(More)
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