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A novel approach for the intravenous delivery of leuprolide using core-cross-linked polymeric micelles.
Polymeric Nanoparticles with Neglectable Protein Corona.
TLDR
It is underlined that polymeric nanoparticles can be synthesized, for which a protein corona formation does not take place, and some proteins are enriched, but their concentration is significantly less than one protein per particle.
Tailoring the physicochemical properties of core-crosslinked polymeric micelles for pharmaceutical applications.
Lyophilization stabilizes clinical‐stage core‐crosslinked polymeric micelles to overcome cold chain supply challenges
TLDR
Docetaxel (DTX)‐entrapped CCPM, also referred to as CPC634, have demonstrated favorable pharmacokinetics, tolerability, and enhanced tumor uptake in patients and clinical efficacy evaluation is ongoing.
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