Qiuyue Zhao

Learn More
miR-449a, a novel tumor suppressor, is deregulated in various malignancies, including prostate cancer. Overexpression of miR-449a induces cell cycle arrest, apoptosis, and senescence, but its role in response to ionizing radiation and underlying molecular mechanism are still unknown. Here, we report that miR-449a enhances radiation-induced G2/M phase arrest(More)
MicroRNAs (miRNAs) have been reported to be involved in DNA damage response induced by ionizing radiation (IR). c-Myc is reduced when cells treated with IR or other DNA damaging agents. It is unknown whether miRNAs participate in c-Myc downregulation in response to IR. In the present study, we found that miR-449a enhanced radiosensitivity in vitro and in(More)
Trust relationships between user pairs play a vital role in making decisions for social network users. In reality, available explicit trust relations are often extremely sparse, therefore, inferring unknown trust relations attracts increasing attention in recent years. In this paper, a new approach originating from machine learning is proposed to predict(More)
  • 1