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Non-small cell lung cancer (NSCLC) exhibits radio-resistance to conventional rays, due to its DNA damage repair systems. NSCLC may potentially be sensitized to radiation treatment by reducing those factors that continuously enhance the repair of damaged DNA. In the present study, normal lung fibroblast MRC-5 and lung cancer A549 cells were treated with(More)
The objective of this study was to assess the clinical efficacy and safety of concomitant or adjuvant tomozolomide with whole-brain irradiation (WBI) in patients with brain metastases. MEDLINE, EMBASE, Cochrane Library, Chinese Biomedical Literature Database were searched to identify relevant original published trails, and the references of eligible studies(More)
OBJECTIVES Radiotherapy for the management of keloids was first introduced in 1906, yet 107 years later optimal protocol has not yet been established. Most studies have been conducted using x-ray, β-ray, or γ-ray. However, for high linear energy transfer radiation, clinical data are scarce. The aim of this study was to examine the efficacy and safety of(More)
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