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Comprehensive Review of Human Sapoviruses
This review focuses on genomic and antigenic features, molecular typing/classification, detection methods, and clinical and epidemiological profiles of human sapoviruses. Expand
New variants of porcine epidemic diarrhea virus with large deletions in the spike protein, identified in the United States, 2016-2017
Four types of porcine epidemic diarrhea virus (PEDV) variants with a large deletion in the spike protein were detected, together with the original US PEDV, from pig fecal and oral fluid samples collected during 2016-2017 in the US, indicating that P EDV continues to evolve in pigs and might be responsible for disease pattern changes. Expand
Distinct Characteristics and Complex Evolution of PEDV Strains, North America, May 2013–February 2014
Sequence analysis showed heterogeneity among 74 strains and distinct molecular characteristics of highly virulent strains and variants.
Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs
Findings confirm that strain PC21A of the virus is highly enteropathogenic and progression of porcine epidemic diarrhea virus infection is understood. Expand
Comprehensive Comparison of Cultivable Norovirus Surrogates in Response to Different Inactivation and Disinfection Treatments
Although inactivation profiles were variable for each treatment, TuV and MNV were the most resistant CSV overall and therefore are the best candidates for studying the public health outcomes of norovirus infections. Expand
Cell culture isolation and sequence analysis of genetically diverse US porcine epidemic diarrhea virus strains including a novel strain with a large deletion in the spike gene
This is the first report of the isolation in cell culture of an S INDEL P EDV strain and a PEDV strain with a large (197aa) deletion in the S protein, and designed primer sets to detect these genetically diverse US PEDv strains. Expand
Isolation and Characterization of Porcine Deltacoronavirus from Pigs with Diarrhea in the United States
This is the first report describing cell culture isolation, serial propagation, and biological and genetic characterization of cell-adapted PDCoV strains, and the information presented is important for the development of diagnostic reagents, assays, and potential vaccines against emergent PD coV strains. Expand
Antigenic Relationships among Porcine Epidemic Diarrhea Virus and Transmissible Gastroenteritis Virus Strains
Evidence of antigenic cross-reactivity between porcine enteric coronaviruses, PEDV and TGEV, in CCIF assays supports the idea that these two species are evolutionarily related, but they are distinct species defined by VN assays. Expand
Evolution, antigenicity and pathogenicity of global porcine epidemic diarrhea virus strains
PEDV can serve as a model to explore the molecular mechanisms of coronavirus evolution and pathogenesis, and the evolution, antigenic relationships and pathologic features of PEDV strains are reviewed. Expand