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BACKGROUND Ubiquitination is a post-translation modification where ubiquitin is attached to a substrate. Ubiquitin-conjugating enzymes (E2s) play a major role in the ubiquitin transfer pathway, as… (More)
The E2 is at the center of a cascade of Ub1 transfers, and it links activation of the Ub1 by E1 to its eventual E3-catalyzed attachment to substrate. Although the genome-wide analysis of this family… (More)
Based on the ADAMS software, we established a whole vehicle model to study its handling stability. It includes the front suspension system, the rear suspension system, the steering system and four… (More)
Ubiquitin-conjugating enzymes (UBCs), which catalyse the transfer of ubiquitin to substrate or E3 ligases, are key enzymes in ubiquitination modifications of target proteins. Current knowledge… (More)
Culture is a very important factor in affecting design and promoting its development, only by deeply rooted in culture could design make progress. The development of the Chinese design has to absorb… (More)