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Genetic alterations in nasopharyngeal carcinoma (NPC) have been reported in previous works. However, it remains unclear whether polymorphisms within the miRNA-target binding sites are associated with individual NPC risk. In this study, new experimental and computational approaches were developed to assess the polymorphism frequency distribution within the(More)
Long non-coding RNAs (lncRNAs) are aberrantly expressed and have important functions in pathological processes. The present study investigated the lncRNA profiles and the effects of curcumin (Cur) on the radiosensitivity of nasopharyngeal carcinoma (NPC) cells. The lncRNA and mRNA profiles of each cell group were described by microarray analysis. Numerous(More)
Volume up scaling enlarges the size of a volume to make feature analysis more accurate and efficient. Linear interpolation, widely used in volume up scaling, result in jagged artifacts around features and losses of high-frequency components. Based on the example-based up scaling framework, this paper presents a new high-quality volume up scaling technique,(More)
Tumor endothelial marker 1 (TEM1) has been identified as a novel surface marker upregulated on the blood vessels and stroma in many solid tumors. We previously isolated a novel single-chain variable fragment (scFv) 78 against TEM1 from a yeast display scFv library. Here, we evaluated the potential applications of scFv78 as a tool for tumor molecular(More)
In this paper, a new integrated design method the Convex Integrated Design (CID) method, is introduced and applied to the design of a semi-active susp'ension system. The closed-loop system is required to simultaneously satisfy four closed-loop performance specifications: car body acceleration, suspension deflection, tire dynamic load and control effort(More)
Enhancer of zeste homolog 2 (EZH2) is a critical component of the polycomb repressive complex 2, which epigenetically represses genes involved in tumorigenesis and is highly expressed in tumors. However, no studies have investigated EZH2 expression and its clinical significance in human pituitary adenomas (PAs). Therefore, we examined the expression pattern(More)
Volume upscaling generates high-resolution volumes from low-resolution volumes to make data exploration more effective. Traditional methods, such as the simple trilinear or cubic-spline interpolation, may blur boundaries of features and lead to jagged artifacts. Inspired by recent progress in image super-resolution with Convolutional Neural Networks (CNN),(More)
The cylindrical permanent magnet is the core part of the permanent-magnet seed-metering device, it can absorb single magnetic powder coated seed. The first, the magnetic induction intensity model of any point in the cylindrical permanent magnet external was established based on the equivalent current model of permanent magnet. The second, the mathematical(More)