Qinru Shi

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Miniature excitatory postsynaptic currents (mEPSCs) were elicited from small numbers of release sites after brief microperfusion of Ba2+ and K+ onto proximal dendritic processes of hippocampal neurons in culture. Temporal summation of closely timed mEPSCs deviated significantly from linearity. The number of instances of closely timed mEPSCs that were also(More)
It is generally accepted that glutamate serves as the neurotransmitter at most excitatory synapses in the mammalian central nervous system (CNS). Synaptic release of glutamate may trigger a fast and a slow excitatory postsynaptic current (EPSC). The slow EPSC is mediated by N-methyl-D-aspartate (NMDA) receptor channels, whereas the fast EPSC is mediated by(More)
Glutamate receptor (GluR) channels are responsible for a number of fundamental properties of the mammalian central nervous system, including nearly all excitatory synaptic transmission, synaptic plasticity, and excitotoxin-mediated neuronal death. Although many human and rodent neuroblast cell lines are available, none has been directly shown to express(More)
Treatment of the human teratocarcinoma line NTera2/c1.D1 (NT2) with retinoic acid induces terminal neuronal differentiation. In a previous study, we found that the neurons obtained in this way express functional N-methyl-D-aspartate (NMDA) and non-NMDA glutamate receptor channels. We now show by reverse transcriptase-polymerase chain reaction and Southern(More)
A universal need in understanding complex networks is the identification of individual information channels and their mutual interactions under different conditions. In neuroscience, our premier example, networks made up of billions of nodes dynamically interact to bring about thought and action. Granger causality is a powerful tool for identifying linear(More)
This paper is mainly concerned with the upper and lower bound of the number of edges an ordered graph can have avoiding a fixed forbidden ordered subgraph H. The only case where a sharp bound has not been discovered is when H has interval chromatic number 2, where H can be represented as a 0-1 matrix P. Let ex < (n, n, P) be the maximum weight of an n by n(More)
Cartesian stiiness is usually described by a 6 6 matrix which is vital in the study of rigid body grasping by m ultiple robot ngers. In this thesis, a closed form expression is derived for evaluating the grasped object stiiness based on the contact geometry and stiiness properties of individual robot ngers. The kinematics of manipulation by elastic ngers is(More)
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