Learn More
OBJECTIVE The objective was to prevent loss of some implicit structural and local contextual information of lung nodules by current one- (1D) or two-dimensional (2D) schemes. MATERIALS AND METHODS The testing data set used in this study consisted of computed tomographic scans from 196 different patients in Jilin Tumor Hospital, which consisted of 8428(More)
OBJECTIVES To test the hypothesis that the sagittal position of the anterior teeth has no effect on pharyngeal airway dimension or hyoid bone position and to investigate the influence of orthodontic retraction of the anterior teeth on each section of pharynx and hyoid position. MATERIALS AND METHODS Forty-four Class I bimaxillary protrusion adults,(More)
Podocyte apoptosis induced by high levels of glucose is a key event in the development and prognosis of diabetic nephropathy (DN). Forkhead transcription factor O1 (FoxO1) has been defined as a critical mediator of oxidative stress in animal models of diabetes and is involved in mitophagy. To test the role of FoxO1 in regulating podocyte apoptosis both in(More)
The study aims to improve the performance of current computer-aided schemes for the detection of lung lesions, especially the low-contrast in gray density or irregular in shape. The relative position between suspected lesion and whole lung is, for the first time, added as a latent feature to enrich current Three-dimensional (3D) features such as shape,(More)
The generation of hyperglycemia-induced mitochondrial reactive oxygen species (ROS) is a key event in diabetic nephropathy development. The forkhead-box class O1 (FoxO1) and peroxisome proliferator-activated receptor γ co-activator 1α (PGC-1α) proteins are implicated in oxidative stress. We investigated the in vivo association of FoxO1 and PGC-1α in renal(More)
A novel algorithm of Three Dimension matrix (3D matrix) pattern based Minimum Within-Class Scatter Support Vector Machines (MCSVMs3Dmatrix) is presented. Combining Minimum Within-Class Scatter Support Vector Machines (MCSVMs) and higher-order tensor technology, decision functions of MCSVMs3Dmatrix are calculated along with three orthogonal directions in the(More)
OBJECTIVE To evaluate the validity and reliability of the cervical vertebral maturation (CVM) method with a longitudinal sample. MATERIALS AND METHODS Eighty-six cephalograms from 18 subjects (5 males and 13 females) were selected from the longitudinal database. Total mandibular length was measured on each film; an increased rate served as the gold(More)
To prevent an intelligent vehicle from departing the lane in the vision-based navigation, an integrated method based on image processing is proposed to detect the road boundary and lane marking synchronously in structural road environment. The feature of the road boundary is extracted by means of gradient magnitude and gradient direction of pixels. And the(More)
We investigated blood nesfatin-1 levels in hypertension patients. We found that fasting plasma nesfatin-1 levels were significantly higher in hypertension patients than in control groups, especially in overweight/obese hypertension patients (4.5 ± 2.1 versus 3.3 ± 1.1 ng/ml, p < 0.01). Body mass index, systolic blood pressure and diastolic blood pressure(More)
Diabetic nephropathy is characterized by inordinate secretion of extracellular matrix (ECM) proteins from mesangial cells (MCs), which is tightly associated with excessive activation of TGF-β signaling. The forkhead transcription factor O1 (FoxO1) protects mesangial cells from hyperglycemia-induced oxidative stress, which may be involved in ameliorating the(More)