Qingzhu Wang

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The study aims to improve the performance of current computer-aided schemes for the detection of lung lesions, especially the low-contrast in gray density or irregular in shape. The relative position between suspected lesion and whole lung is, for the first time, added as a latent feature to enrich current Three-dimensional (3D) features such as shape,(More)
A novel algorithm of Three Dimension matrix (3D matrix) pattern based Minimum Within-Class Scatter Support Vector Machines (MCSVMs3Dmatrix) is presented. Combining Minimum Within-Class Scatter Support Vector Machines (MCSVMs) and higher-order tensor technology, decision functions of MCSVMs3Dmatrix are calculated along with three orthogonal directions in the(More)
MicroRNAs play important roles in the pathogenesis of diabetic nephropathy (DN). In this study, we found that high glucose upregulated miR-27a expression in cultured glomerular mesangial cells and in the kidney glomeruli of streptozotocin (STZ)-induced diabetic rats. miR-27a knockdown prevented high glucose-induced mesangial cell proliferation and also(More)
BACKGROUND The incidence of thyroid cancer has progressively increased over the past few decades, and the most frequent types of this cancer are papillary thyroid carcinoma (PTC) and small primary tumors. In PTC, oncogene activation is known to occur at a high frequency. However, the potential roles of tumor suppressor genes in thyroid carcinogenesis remain(More)
The generation of hyperglycemia-induced mitochondrial reactive oxygen species (ROS) is a key event in diabetic nephropathy development. The forkhead-box class O1 (FoxO1) and peroxisome proliferator-activated receptor γ co-activator 1α (PGC-1α) proteins are implicated in oxidative stress. We investigated the in vivo association of FoxO1 and PGC-1α in renal(More)
Tensor Compressive Sensing (CS) is an emerging approach for higher order data representation, such as medical imaging, video sequences and multi-sensor networks. In this paper, we propose an Adaptive Tensor CS (ATCS) scheme for Three-dimensional (3D) images, especially those which contain noise. First, we find the relationship between reconstruction(More)
An Active Appearance Model (AAM) is a computer vision model which can be used to effectively segment lung fields in CT images. However, the fitting result is often inadequate when the lungs are affected by high-density pathologies. To overcome this problem, we propose a Higher-order Singular Value Decomposition (HOSVD)-based Three-dimensional (3D) AAM. An(More)
BACKGROUND The existing techniques for simultaneous encryption and compression of images refer lossy compression. Their reconstruction performances did not meet the accuracy of medical images because most of them have not been applicable to three-dimensional (3D) medical image volumes intrinsically represented by tensors. METHODS We propose a tensor-based(More)
Forkhead box P3 (FoxP3) expression in papillary thyroid carcinoma (PTC) is associated with resistance to radioiodine treatment. The sodium iodine symporter (NIS) is a plasma membrane glycoprotein, the repression of which may render the tumor refractive to radioiodine therapy. In this study, samples from 90 PTCs as well as 40 normal thyroid tissues were(More)