Qingyuan Zhang

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Forest canopies are composed of photosynthetically active vegetation (PAV, chloroplasts) and nonphotosynthetic vegetation (NPV, e.g., cell wall, vein, branch). The fraction of photosynthetically active radiation (PAR) absorbed by the canopy (FAPAR) should be partitioned into FAPARPAV and FAPARNPV. Gross primary production (GPP) of forests is affected by(More)
BACKGROUND mTOR inhibition reverses trastuzumab resistance via the hyperactivated PIK/AKT/mTOR pathway due to PTEN loss, by sensitising PTEN-deficient tumours to trastuzumab. The BOLERO-1 study assessed the efficacy and safety of adding everolimus to trastuzumab and paclitaxel as first-line treatment for patients with HER2-positive advanced breast cancer.(More)
BACKGROUND The intake of soy isoflavones among women with breast cancer has become a public health concern, because these compounds have weak estrogenic effects. There is little clinical evidence about their safety for patients with breast cancer who are receiving adjuvant endocrine therapy. METHODS For patients who underwent surgery for breast cancer(More)
Triple-negative breast cancer (TNBC) has a poor prognosis and lacks prognostic indicators. The androgen receptor (AR) and E-cadherin are involved in the pathogenesis of breast cancer, but their roles are not clearly defined. We designed this study to evaluate AR and E-cadherin expression and to determine their relationships with the clinicopathologic(More)
In this paper, we present a theoretical and modeling framework to estimate the fractions of photosynthetically active radiation (PAR) absorbed by vegetation canopy (FAPARcanopy), leaf (FAPARleaf ), and chlorophyll (FAPARchl), respectively. FAPARcanopy is an important biophysical variable and has been used to estimate gross and net primary production.(More)
The aim of this study was to investigate expression of CD147 and MMP-9 in triple-negative breast cancer (TNBC) so as to determine whether these two proteins may be correlated with poor prognosis of TNBC patients. We examined the expression levels of the CD147 and MMP-9 in 127 patients with TNBC and 30 patients with mammary gland fibroma using(More)
Expression cloning was used to initially isolate the reversion-inducing cysteine-rich protein with Kazal motifs (RECK) gene as a suppressor of transformation. The gene was found to encode a membrane-anchored regulator of MMPs. Experimental studies showed that RECK can suppress tumor invasion, metastasis, and angiogenesis. However, the clinical impact of(More)
BACKGROUND Women with breast cancer treated with aromatase inhibitors (AIs) may experience musculoskeletal symptoms that lead to discontinuation of effective therapy. The purpose of the current study is to evaluate the clinical and genetic predictors for AIs-related musculoskeletal adverse events(MS-AEs). METHODOLOGY AND PRINCIPAL FINDINGS We recruited(More)
Satellite observations play an important role in characterization of the interannual variation of vegetation. Here, we report anomalies of two vegetation indices for Northern Asia (40jN–75jN, and 45jE–179jE), using images from the SPOT-4 VEGETATION (VGT) sensor over the period of April 1, 1998 to November 20, 2001. The Normalized Difference Vegetation Index(More)
Leaf phenology of tropical evergreen forests affects carbon and water fluxes. In an earlier study of a seasonally moist evergreen tropical forest site in the Amazon basin, time series data of Enhanced Vegetation Index (EVI) from the VEGETATION and Moderate Resolution Imaging Spectroradiometer (MODIS) sensors showed an unexpected seasonal pattern, with(More)