Qingyuan Wang

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BACKGROUND Our previous studies showed a down-regulation of GRIM-19 in primary human cervical cancers, and restoration of GRIM-19 induced tumor regression. The induction of tumor suppressor protein p53 ubiquitination and degradation by E6 oncoportein of high risk-HPV through forming a stable complex with E6AP is considered as a critical mechanism for(More)
BACKGROUND The changes of hemodynamics and drug concentration distribution caused by the implantation of drug eluting stents (DESs) in curved vessels have significant effects on In-Stent Restenosis. METHODS A 3D virtual stent with 90° curvature was modelled and the distribution of wall shear stress (WSS) and drug concentration in this model were(More)
With reduced environmental impact becoming an increasingly important benefit of the rail transportation mode, continual improvement in efficiency and reduced energy consumption has become a major concern to rail transit operators. For electrified rail transit operations, regenerative braking is one practical way for saving energy because it enables the(More)
Railway systems may be interrupted by unforeseen events that require quick replanning to a feasible new schedule. This paper deals with the train rescheduling problem on double-track lines. The rescheduling problem is regarded as a conflict detection and resolution procedure. Timed Colored Petri nets are adopted to model the railway system: places represent(More)
Foamed mortar with a density of 1300 kg/m 3 was prepared. In the initial laboratory trials, water-to-cement (w/c) ratios ranging from 0.54 to 0.64 were tested to determine the optimal value for foamed mortar corresponding to the highest compressive strength without compromising its fresh state properties. With the obtained optimal w/c ratio of 0.56, two(More)
Implantation of drug-eluting stents in curved blood vessels may cause changes in hemodynamics and drug distribution, and even provoke in-stent restenosis. Due to the complexity of building three-dimensional (3-D) curved stent model, few studies have gone through such numerical simulations. In this study, three virtual stent models with different bending(More)
Hybrid visceral-renal debranching procedures with endovascular repair have been proposed as an appealing technique to treat conventional thoracoabdominal aortic aneurysm (TAAA). This approach, however, still remained controversial because of the non-physiological blood flow direction of its retrograde visceral revascularization (RVR) which is generally(More)
BACKGROUND The changes of hemodynamics caused by the implantation of multilayer stent (MS) have significant effects for aneurysm sac. METHODS Comparisons of 3D numerical models with/without a MS in an abdominal aortic aneurysm with a 90° branch vessel were numerically studied from the viewpoint of hemodynamics. RESULTS The results showed that: (1) The(More)
OBJECTIVE To measure setup error of head and neck neoplasm in radiotherapy and discuss over effects of error on physical dose acting on target region and organs at risk of nasopharynx cancer (NPC) patients treated with intensity modulated radiation therapy (IMRT). METHODS A total of 152 patients who developed head and neck neoplasm and received IMRT were(More)