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- Influence
Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro
- Yaoxing Wu, Qingxiang Liu, +5 authors J. Cui
- Biology, Medicine
- Cell Discovery
- 21 March 2017
Type I interferon (IFN) serves as the first line of defense against invading pathogens. Inhibition of IFN-triggered signaling cascade by Zika virus (ZIKV) plays a critical role for ZIKV to evade… Expand
TRIM9 short isoform preferentially promotes DNA and RNA virus-induced production of type I interferon by recruiting GSK3β to TBK1
- Yunfei Qin, Qingxiang Liu, Shuo Tian, W. Xie, J. Cui, R. Wang
- Biology, Medicine
- Cell Research
- 26 February 2016
Type I interferon (IFN) is an important component of antiviral innate immune signaling mediated by viral DNA and RNA recognition by the DNA sensor cGAS and RNA sensors RIG-I and MDA5. Activation of… Expand
Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1‐caspase‐1 axis
- Y. Zheng, Qingxiang Liu, +7 authors J. Cui
- Biology, Medicine
- The EMBO journal
- 14 September 2018
Viral infection triggers host innate immune responses, which primarily include the activation of type I interferon (IFN) signaling and inflammasomes. Here, we report that Zika virus (ZIKV) infection… Expand
Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro
- Yaoxing Wu, Qingxiang Liu, +5 authors J. Cui
- Medicine
- Cell Discovery
- 11 April 2017
[This corrects the article DOI: 10.1038/celldisc.2017.6.].
LRRC25 inhibits type I IFN signaling by targeting ISG15‐associated RIG‐I for autophagic degradation
- Yang Du, Tianhao Duan, +4 authors R. Wang
- Biology, Medicine
- The EMBO journal
- 1 February 2018
The RIG‐I‐like receptors (RLRs) are critical for protection against RNA virus infection, and their activities must be stringently controlled to maintain immune homeostasis. Here, we report that… Expand
Fluoride-driven ‘turn on’ ESPT in the binding with a novel benzimidazole-based sensor
- K. Liu, X. Zhao, Qingxiang Liu, J. Huo, Bolin Zhu, Shihua Diao
- Chemistry, Medicine
- Beilstein journal of organic chemistry
- 24 April 2015
Summary A novel fluorescence sensor (BIP) bearing NH and OH subunits displayed a highly selective and sensitive recognition property for fluoride over other anions. Fluoride-driven ESPT, poorly used… Expand
Programmed cell death is responsible for replaceable bud senescence in chestnut (Castanea mollissima BL.)
- Guangpeng Wang, Z. Zhang, Dejun Kong, Qingxiang Liu, G. Zhao
- Biology, Medicine
- Plant Cell Reports
- 3 June 2012
AbstractIn the chestnut “replaceable bud” cultivar ‘Tima zhenzhu’, the auxiliary bud formed on the fruiting branch dies after fruiting, giving rise to a morphology more suitable than the wild type’s… Expand
An IoT-Oriented data placement method with privacy preservation in cloud environment
- Xiaolong Xu, Shucun Fu, +4 authors Shancang Li
- Computer Science
- J. Netw. Comput. Appl.
- 15 December 2018
TLDR
Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses
- Qingxiang Liu, Yaoxing Wu, +4 authors J. Cui
- Biology, Medicine
- Science Advances
- 1 May 2018
Deubiquitinase family proteins are broadly involved in modulating antiviral response through dynamic and diverse mechanisms. The innate immune response conferred by type I interferons is essential… Expand
Stratified ubiquitination of RIG-I creates robust immune response and induces selective gene expression
- Huifang Xian, W. Xie, +5 authors J. Cui
- Biology, Medicine
- Science Advances
- 1 September 2017
Stratified multisite ubiquitination of RIG-I provides a robust and optimal control of innate antiviral responses. The activation of retinoic acid–inducible gene I (RIG-I), an indispensable viral RNA… Expand
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