Qingsong Liu

Publications8
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Citations92
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Synthesis and Evaluation of the Cytotoxicity of Apoptolidinones A and D
TLDR
The aglycones apoptolidinone A and D were shown to be noncytotoxic when evaluated against human lung cancer cells (H292) and the efficient synthetic strategy leading to the apoptolid inones features construction of the common 20-membered macrolactone by an intramolecular Suzuki reaction and stereocontrolled aldol reactions.
Total synthesis of apoptolidinone.
Development of an end-game strategy towards apoptolidin: a sequential Suzuki coupling approach
Studies on the Synthesis of Apoptolidin: Progress on the Stereocontrolled Assembly of the Pseudo Aglycone of Apoptolidin
Progress on a stereocontrolled total synthesis of the pseudo aglycone of apoptolidin (2) starting from (S)-epichlorohydrin is reported. The lower C(12)–C(28) fragment (4) was derived by consecutive…
Large scale total synthesis of apoptolidinone and progress towards the total synthesis of ammocidin
Development of an End‐Game Strategy Towards Apoptolidin: A Sequential Suzuki Coupling Approach.
Total Synthesis of Apoptolidinone.
Synthesis and Evaluation of the Cytotoxicity of Apoptolidinones A and D.