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Does music therapy enhance behavioral and cognitive function in elderly dementia patients? A systematic review and meta-analysis
Subgroup analyses showed that disease sub-type, intervention method, comparator, subject location, trial design, trial period and outcome measure instrument made little difference in outcomes; the meta-regression may have identified the causes of heterogeneity as the intervention method , comparator and trial design. Expand
Protective Effects of Arctium lappa L. Roots Against Hydrogen Peroxide-Induced Cell Injury and Potential Mechanisms in SH-SY5Y Cells
Findings suggest that EAL may be regarded as a potential antioxidant agent and possess potent neuroprotective activity against H2O2-induced injury. Expand
Pterocarine, a New Diarylheptanoid from Pterocarya tonkinesis, Its Cell Cycle Inhibition at G0/G1 Phase and Induction of Apoptosis in HCT-15 and K562 Cells
Pterocarine (1), a new diarylheptanoidal compound, was isolated from Pterocarya tonkinesis (Franch.) Dode. together with a known diarylheptanoid, myricatomentogenin (2), through a bioassay-guidedExpand
Evaluation of the wound-healing activity and anti-inflammatory activity of aqueous extracts from Acorus calamus L.
Results showed significantly the wound-healing activity of aqueous extracts in the animal model of excise wound healing, and anti-inflammatory activity in vitro. Expand
Notopterygium incisum extract (NRE) rescues cognitive deficits in APP/PS1 Alzhneimer's disease mice by attenuating amyloid-beta, tau, and neuroinflammation pathology.
It is demonstrated that NRE has a potential anti-AD effect via the inhibition of the Aβ cascade, tau pathology and neuroinflammation in vitro and in vivo. Expand
Neuroprotective effects of Kukoamine B against hydrogen peroxide-induced apoptosis and potential mechanisms in SH-SY5Y cells.
Investigation of the protective effects of Kukoamine B against hydrogen peroxide induced cell injury and potential mechanisms in SH-SY5Y cells revealed that treatment with KuB prior to H2O2 exposure effectively increased the cell viability, and restored the mitochondria membrane potential (MMP). Expand
Novel ADAM-17 inhibitor ZLDI-8 enhances the in vitro and in vivo chemotherapeutic effects of Sorafenib on hepatocellular carcinoma cells
Results suggest that ZLDI-8 can be a promising therapeutic agent to enhance Sorafenib’s anti-tumor effect and to overcome the MDR of HCC patients. Expand
A novel inhibitor of ADAM17 sensitizes colorectal cancer cells to 5‐Fluorouracil by reversing Notch and epithelial‐mesenchymal transition in vitro and in vivo
This study aimed to discover a novel ADAM17 inhibitor and investigate the chemosensitization effect in colorectal cancer patients with poor prognosis with chemotherapy. Expand
Neuroprotective effects of Arctium lappa L. roots against glutamate-induced oxidative stress by inhibiting phosphorylation of p38, JNK and ERK 1/2 MAPKs in PC12 cells.
Protective effects of ethyl acetate extract of Arctium lappa L. roots against glutamate-induced oxidative stress in PC12 cells were evaluated and indicate that EAE may be a promising neuroprotective agent for the prevention and treatment of neurodegenerative diseases implicated with oxidative stress. Expand
Comparative efficacy and tolerability of probiotics for antibiotic-associated diarrhea: Systematic review with network meta-analysis
Lactobacillus casei appears to be the most efficacious choice when associated with severe C. difficile-related cases, and is probably the best option to consider when AAD is indicated. Expand