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Bone metastasis is common in lung cancer patients and associated with reduced quality of life and reduced overall and median survival, so the early detection of bone metastasis and monitoring of its status is very important for clinicians. Serum bone-specific alkaline phosphatase (BAP), osteocalcin (OC), beta isomer of C-terminal telopeptide of type I(More)
OBJECTIVE To study which markers can be applied to monitor the presence of the bone metastases in primary lung cancer without bone lesion during the follow-up period. METHODS Based on the criteria for inclusion, we screened and selected 10 cases of lung cancer with bone metastases, 10 cases of lung cancer without bone metastases and 10 healthy subjects.(More)
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