Learn More
Long QT syndrome (LQT) is an inherited disorder that causes sudden death from cardiac arrhythmias, specifically torsade de pointes and ventricular fibrillation. We previously mapped three LQT loci: LQT1 on chromosome 11p15.5, LQT2 on 7q35-36, and LQT3 on 3p21-24. Here we report genetic linkage between LQT3 and polymorphisms within SCN5A, the cardiac sodium(More)
Software defect prediction helps to optimize testing resources allocation by identifying defect-prone modules prior to testing. Most existing models build their prediction capability based on a set of historical data, presumably from the same or similar project settings as those under prediction. However, such historical data is not always available in(More)
Recent works in the area of stroke and brain ischemia has demonstrated the significance of the inflammatory response accompanying necrotic brain injury. Acutely, this response appears to contribute to ischemic pathology, and anti-inflammatory strategies have become popular. This chapter will discuss the current knowledge of the contribution of systemic and(More)
—Device-to-Device (D2D) communication was initially proposed in cellular networks as a new paradigm to enhance network performance. The emergence of new applications such as content distribution and location-aware advertisement introduced new use-cases for D2D communications in cellular networks. The initial studies showed that D2D communication has(More)
—A new universal estimator of divergence is presented for multidimensional continuous densities based on k-nearest-neighbor (k-NN) distances. Assuming independent and identically distributed (i.i.d.) samples, the new estimator is proved to be asymptotically unbiased and mean-square consistent. In experiments with high-dimensional data, the k-NN approach(More)
We propose an object tracking algorithm that learns a set of appearance models for adaptive discriminative object representation. In this paper, object tracking is posed as a binary classification problem in which the correlation of object appearance and class labels from foreground and background is modeled by partial least squares (PLS) analysis, for(More)
Pancreatic cancer is a disease with an extremely poor prognosis. Tumor protein 53-induced nuclear protein 1 (TP53INP1) is a proapoptotic stress-induced p53 target gene. In this article, we show by immunohistochemical analysis that TP53INP1 expression is dramatically reduced in pancreatic ductal adenocarcinoma (PDAC) and this decrease occurs early during(More)
In recent years, governments, standardization bodies, automobile manufacturers, and academia are working together to develop vehicular ad hoc network (VANET)-based communication technologies. VANETs apply multiple channels, i.e., control channel (CCH) and service channels (SCHs), to provide open public road safety services and the improve comfort and(More)