Learn More
Bacteria play an important role in the decomposition and cycling of a variety of compounds in freshwater aquatic environments, particularly nutrient-rich eutrophic lakes. A unique Chinese eutrophic lake--Dianchi--was selected for study because it has two separate and distinct basins, Caohai with higher organic carbon levels and Waihai with lower organic(More)
Hedgehog transduces signal by promoting cell surface expression of the seven-transmembrane protein Smoothened (Smo) in Drosophila, but the underlying mechanism remains unknown. Here we demonstrate that Smo is downregulated by ubiquitin-mediated endocytosis and degradation, and that Hh increases Smo cell surface expression by inhibiting its ubiquitination.(More)
The immunomodulatory and anti-oxidative activities of differentiated mesenchymal stem cells contribute to their therapeutic efficacy in cell-replacement therapy. Mesenchymal stem cells were isolated from human umbilical cord and induced to differentiate with basic fibroblast growth factor, nerve growth factor, epidermal growth factor, brain-derived(More)
Dianchi Lake is a typical Chinese eutrophic lake. The bacterial community in the polluted water of the Dianchi lakeshore was investigated by cultivation-independent approaches. The amplicon length heterogeneity polymerase-chain reaction (LH-PCR) was used to detect the major differences in bacterial structure among the nine different sampling sites. Cluster(More)
Fabricated vessel-mimetic microtubes are essential for delivering sufficient nutrient to engineered composite tissues. In this paper, vascular-like microtubes are engineered by automated assembly of donut-shaped micromodules that embed fibroblast cells. A microrobotic system is set up with dual manipulators of 30-nm positioning resolution under an optical(More)
The 3D assembly of micro-/nano-building blocks with multi-nanomanipulator coordinated manipulation is one of the central elements of nanomanipulation. A novel rail-guided nanomanipulation system was proposed for the assembly of a cellular vascular-like hydrogel microchannel. The system was equipped with three nanomanipulators and was restricted on the rail(More)
We explored the regulation of erythropoietin and erythropoietin receptor on traumatic brain injury (TBI), as well as the antiapoptotic effects of recombinant human erythropoietin (rhEPO) treatment. Female Wistar rats were randomly divided into three groups: rhEPO-treated TBI, vehicle-treated TBI, and sham-operated. TBI was induced by the Feeney free falling(More)
Environmental monitoring robot is a new method for approaching environmental monitoring. The main issue with the development of this is to develop accessible its system. Several studies have been conducted on the autonomous monitoring system and they performed well, however, almost they are costly and complex therefore be not considered well to be(More)
Fabrication of artificial blood vessels in micro scale significantly benefits the regeneration of functional human vascular networks. In this paper, we develop an efficient multi-microrobotic system with an innovative motorized sample holder (MSH) and two manipulators. Air is injected into the solution through a glass pipette fixed on one manipulator to(More)