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UNLABELLED The Inveon dedicated PET (DPET) scanner is the latest generation of preclinical PET systems devoted to high-resolution and high-sensitivity murine model imaging. In this study, we report on its performance based on the National Electrical Manufacturers Association (NEMA) NU-4 standards. METHODS The Inveon DPET consists of 64 lutetium(More)
UNLABELLED The National Electrical Manufacturers Association (NEMA) standard NU 4-2008 for performance measurements of small-animal tomographs was recently published. Before this standard, there were no standard testing procedures for preclinical PET systems, and manufacturers could not provide clear specifications similar to those available for clinical(More)
We report on large energy pulse generation in an erbium-doped fiber laser passively mode-locked with atomic layer graphene. Stable mode locked pulses with single pulse energy up to 7.3 nJ and pulse width of 415 fs have been directly generated from the laser. Our results show that atomic layer graphene could be a promising saturable absorber for large energy(More)
PURPOSE The traditional figures of merit used in the evaluation of positron emission tomography (PET) systems, including system sensitivity and spatial resolution, do not directly reflect the minimum detectable activity (MDA) performance, despite the fact that it is one of the most important tasks for a PET system. MDA, as a combination of the more(More)
The objectives of this study were to screen probiotic characteristics of lactobacilli isolated from traditionally homemade koumiss products in Xinjiang and Inner Mongolia of China, and to determine and compare the effect of the Lactobacillus strains in vivo on lipid metabolism in rats fed with a high-lipid diet. Three out of 68 strains of Lactobacillus(More)
PETbox is a low cost bench top preclinical PET scanner dedicated to pharmacokinetic and pharmacodynamic mouse studies. A prototype system was developed at our institute, and this manuscript characterizes the performance of the prototype system. The PETbox detector consists of a 20 × 44 bismuth germanate crystal array with a thickness of 5 mm and(More)
PETbox, an integrated low-cost benchtop preclinical PET scanner dedicated to high throughput quantitative mouse studies is currently under development at the Crump Institute for Molecular Imaging, UCLA. The system employs two opposing flat panel BGO detector blocks on a static gantry and produces a limited number of projection angles around a central(More)
Novel molecular imaging applications increasingly involve studies where very low amount of activity is present. This operation point can be challenging in terms of image quality especially when the intrinsic detector activity from scintillators such as LSO is considered. LSO crystals contain <sup>176</sup>Lu which emits beta<sup>-</sup> particles followed(More)
Bioluminescence imaging, especially planar bioluminescence imaging, has been extensively applied in in vivo preclinical biological research. Bioluminescence tomography (BLT) has the potential to provide more accurate imaging information due to its 3D reconstruction compared with its planar counterpart. In this work, we introduce a positron emission(More)
BACKGROUND Total skin electron irradiation (TSEI) is a special radiotherapy technique which has generally been used for treating adult patients with mycosis fungoides. Recently, two infants presented with leukemia cutis isolated to the skin requiring TSEI. This work discusses the commissioning and quality assurance (QA) methods for implementing a modified(More)