Qin Tian

Learn More
Ischemic heart disease (IHD) is a leading cause of death worldwide. Urban public health and medical management in Shenzhen, an international city in the developing country of China, is challenged by an increasing burden of IHD. This study analyzed the spatio-temporal variation of IHD hospital admissions from 2003 to 2012 utilizing spatial statistics,(More)
Research on spatial cluster detection of traffic crash (TC) at the city level plays an essential role in safety improvement and urban development. This study aimed to detect spatial cluster pattern and identify riskier road segments (RRSs) of TC constrained by network with a two-step integrated method, called NKDE-GLINCS combining density estimation and(More)
Several studies have demonstrated the rabies virus to be a perfect potential vaccine vector to insert foreign genes into the target genome. For this study, a green fluorescent protein (GFP) gene was cloned into the rabies virus (RABV) genome between the N and P gene. CT dinucleotide was inserted as intergenic region. The recombinant high egg passage Flury(More)
Rabies remains a major public health concern in many developing countries. The precise neuropathogenesis of rabies is unknown, though it is hypothesized to be due to neuronal death or dysfunction. Mice that received intranasal inoculation of an attenuated rabies virus (RABV) strain HEP-Flury exhibited subtle clinical signs, and eventually recovered, which(More)
With the coming era of big data and the rapid development and widespread applications of Geographical Information Systems (GISs), geocoding technology is playing an increasingly important role in bridging the gap between non-spatial data resources and spatial data in various fields. However, Chinese geocoding faces great challenges because of the complexity(More)
We present a two-step method for scarless–markerless genome genetic modification in Salmonella enterica based on the improved suicide plasmid pGMB152. The whole LacZYA gene can provide a lacZ-based blue/white screening strategy for fast selection of double-crossover mutants by allelic exchange. The high efficiency of this genetic engineering strategy(More)
  • 1