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Ligustrum lucidum Ait. fruit extract induces apoptosis and cell senescence in human hepatocellular carcinoma cells through upregulation of p21.
Observations suggest that Nü-zhen-zi is a potential anticancer herb and support the traditional use of Nü/Zinc tonifying Chinese herbs for hepatocarcinoma treatment. Expand
A CAPE analogue as novel antiplatelet agent efficiently inhibits collagen-induced platelet aggregation.
Findings suggest that the inhibitory mechanism of CAPE-NO2 on collagen-induced platelet aggregation might be associated with the down-regulation of TXB2, COX-1 and 5-HT and the elevation of NO and cGMP production, which are closely related to platelet function. Expand
Research Progress in the Application of Chinese Herbal Medicines in Aquaculture: A Review
Abstract Due to increasing safety concerns regarding human consumption of fish products, an increasing number of medicinal chemicals are prohibited from use in aquaculture. As a result, Chinese… Expand
Principles and Scientific Basis of Traditional Chinese Medicine in Cancer Treatment
There is a great need to explore the combination rule ofAnti-cancer herbs, and establish effective herbal formulas for various situations in cancer treatment, and emphasize application of anti-cancer herb must guided by TCM principles. Expand
[Effects of resveratrol on apoptosis and ROS production in Hepa 1-6 hepatocarcinoma cells].
- Qin Du, K. Shen, B. Hu, S. Deng
- Chemistry, Medicine
- Zhong yao cai = Zhongyaocai = Journal of Chinese…
- 1 March 2012
Resveratrol could inhibit cell proliferation, induce apoptosis in murine hepatocarcinoma Hepa 1-6 cells, and the mechanism may associated with caspase-3 activation and ROS production. Expand
Nanoparticle-mediated RNA interference of angiotensinogen decreases blood pressure and improves myocardial remodeling in spontaneously hypertensive rats.
- L. Yuan, Jing Sheng, P. Lu, Yuqiang Wang, T. Jin, Qin Du
- Biology, Medicine
- Molecular medicine reports
- 1 September 2015
It is shown that AGT‑silencing had a significant inhibitory effect on hypertension and hypertensive‑induced cardiac hypertrophy in SHRs. Expand
Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells.
The results showed that curcumin and resveratrol significantly inhibited the proliferation of Hepa1-6 cells in a dose- and time-dependent manner, and prompted new insights into the effective mechanism of paired-herbs in traditional Chinese medicine. Expand
Traditional Chinese medicine for prevention and treatment of hepatocarcinoma: From bench to bedside.
Clinical practices have confirmed that TCM is effective to alleviate clinical symptoms, improve quality of life and immune function, prevent recurrence and metastasis, delay tumor progression, and prolong survival time in hepatocarcinoma patients. Expand
Tachykinin NK2 Receptor and Functional Mechanisms in Human Colon: Changes with Indomethacin and in Diverticular Disease and Ulcerative Colitis
- E. Burcher, F. Shang, +4 authors Lu Liu
- Journal of Pharmacology and Experimental…
- 1 January 2008
In circular muscle strips, indomethacin enhanced contractile responses to NKA and to the NK2 receptor-selective agonist [Lys5,MeLeu9,Nle10]-NKA(4–10) in both normal and acute diverticular disease specimens, indicating NK1 receptor-mediated release of relaxant prostanoids. Expand
Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5 - Fluorouracil in CT26 colon carcinoma
TLBZT exhibited significantly anticancer effect, and enhanced the effects of 5-Fu in CT26 colon carcinoma, which may correlate with induction of apoptosis and cell senescence, and angiogenesis inhibition. Expand