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BACKGROUND The aim of this study was to investigate the feasibility of an alternative approach to electronic pacemaker by using spontaneously excitable cell grafts as a biological pacemaker in a large animal model of complete atrioventricular block. METHODS AND RESULTS Dissociated male human atrial cardiomyocytes including sinus nodal cells were grafted(More)
BACKGROUND Sinus node dysfunction and severe heart block are major indications for electronic pacemaker implantation. The aim of the present study was to investigate the feasibility of an alternative approach by using spontaneously excitable cell grafts to serve as a biological pacemaker. METHODS Enzymatically isolated neonatal atrial cardiomyocytes(More)
There is a growing interest in characterizing functional specialization along the long axis of the hippocampus in humans. Variability in volumetry along the long axis of the hippocampus may be of functional relevance in human development, and in a number of clinical populations. However, there is a lack of consistent definitions for measurements of regional(More)
submitted to 2017 American Psychological Association conference Introduction: Differences in resting state functional connectivity (RSFC), particularly in the Default Mode Network (DMN), have been observed in persons at risk for Alzheimer’s disease (AD). We investigated the relationship between RSFC of the posterior cingulate cortex (PCC), a region(More)
An individual's socioeconomic status (SES) is often viewed as a proxy for a host of environmental influences. SES disparities have been linked to variance in brain structures particularly the hippocampus, a neural substrate of learning and memory. However, it is unclear whether the association between SES and hippocampal volume is similar in children and(More)
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