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PURPOSE To define the alterations of corneal nerves in aqueous tear deficiency dry eye patients with or without Sjögren syndrome and to identify the relationship between the morphologic changes of corneal nerves and the extent of dry eye. METHODS Confocal microscopy was used to examine 38 consecutive aqueous tear deficiency patients (8 Sjögren syndrome(More)
Squamous metaplasia is a common pathological process that occurs in the ocular surface epithelium. At present, there is no effective treatment for this abnormality. In the current study, we established an ex vivo conjunctival squamous metaplasia model by culturing human conjunctival tissues at an air-liquid interface for durations of up to 12 days. We then(More)
OBJECTIVE To evaluate tear film changes after phacoemulsification. METHODS This prospective randomized study involved 68 consecutive patients with age-related cataract (79 eyes) who underwent phacoemulsification. Tear break-up time, Schirmer I test (S I t) value, corneal fluorescein staining, tear film pattern by DR-1 tear interfermetry and the height of(More)
PURPOSE Inflammation and squamous metaplasia is a common pathological process that occurs in many ocular surface diseases such as dry eye, Stevens-Johnson syndrome, mucous membrane pemphigoid, and chemical/thermal burns. At present, there is no ideal medicinal treatment for this abnormality. We report herein on an ex vivo conjunctival inflammation and(More)
OBJECTIVE To investigate the effects and mechanism of amniotic extraction on corneal healing after photorefractive keratectomy (PRK). METHODS Experimental Study. Thirty-six New Zealand rabbit corneas were performed with PRK models (-10 diopters, 6.5 mm diameter). According to random number table, all eyes were divided into three groups, including treated(More)
OBJECTIVE To investigate the anti-angiogenesis effects of recombinant human kringle 5 (rhk5) eye drops on corneal neovascularization (CNV) in rabbits induced by alkali burn. METHODS Forty New Zealand albino rabbits were burned on the central corneas of their right eyes by 1 mol/L NaOH for 60s. Animals were randomly divided into 4 groups, 10 rabbits each(More)
OBJECTIVE To evaluate the effects of corrective surgery in adult strabismic patients with visual deficits and the stability of postoperative alignments. METHODS Retrospective study. Alignment and binocular visual function were evaluated in adult patients with visual deficits (best corrective visual acuity (BCVA) <0.3 in one or both eyes) with at least 6(More)
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