Qichang Zhou

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OBJECTIVES To investigate changes in fetal myocardial deformation in intrahepatic cholestasis of pregnancy. METHODS Patients with intrahepatic cholestasis of pregnancy were divided into 2 groups according to the total maternal serum bile acid concentration: mild cholestasis (10-40 μmol/L) and severe cholestasis (>40 μmol/L). Fetal echocardiography and(More)
OBJECTIVE To determine the role of toll-like receptor 2 in cardiac dysfunction during polymicrobial sepsis. DESIGN Controlled animal study. SETTING University hospital research laboratory. SUBJECTS Male C57BL/6, wild-type, toll-like receptor 2-/-. INTERVENTION Polymicrobial peritonitis, a clinically relevant model of sepsis, was generated by cecum(More)
OBJECTIVE The objective of this study is to evaluate the prenatal diagnosis of ventricular non-compaction cardiomyopathy (NCCM) and to report the pathologic features and the characteristic myocardial ultrastructure of fetal NCCM. METHOD We examined nine cases of fetal NCCM by prenatal echocardiography from 2004 to 2013. These cases were evaluated with(More)
OBJECTIVE To construct Z-score reference ranges for normal fetal heart sizes throughout pregnancy. METHODS This is a prospective cross-sectional investigation of 809 normal singleton fetuses from 11th week to term. Fetal transverse heart diameter (HD), heart length (HL), heart circumference (HC) and heart area (HA) were derived from two-dimensional(More)
BACKGROUND Toll-like receptor 4 (TLR4), the receptor for endotoxin, mediates hyperinflammatory response and contributes to high mortality during both endotoxin shock and severe sepsis. However, little is known about the role of TLR4 in the pathogenesis of low-grade polymicrobial sepsis, which is often associated with immunosuppression. METHODS Low-grade(More)
OBJECTIVE To determine the value of contrast-enhanced ultrasound in the diagnosis of benign and malignant hepatic tumors. METHODS A total of 83 patients with 123 focal liver lesions (FLLs) underwent contrast enhanced ultrasound (CEUS) examination. The contrast enhanced characterization of FLLs were compared. RESULTS All the 103 lesions in hepatocallular(More)
PURPOSE This study aimed to determine the role of breast invasive ductal cancer (BIDC) size measured with Contrast-enhanced Ultrasound (CEUS) in the prediction of regional lymph node metastasis (LNM) and N stage. METHODS One hundred and six consecutive patients with breast lesions underwent ultrasound imaging within 2 weeks before mastectomy and axillary(More)
OBJECTIVES This study aimed to establish reference ranges for Doppler parameters of the fetal dorsalis pedis artery and to compare them with those of the anterior tibial artery. METHODS Dorsalis pedis artery velocimetry was performed in 138 singleton fetuses. Intraobserver repeatability coefficients and differences between measurements of bilateral legs(More)
OBJECTIVE The goal of our study was to evaluate the evolution of cardiac findings and assess the pregnancy outcome of fetuses with cardiac asymmetry at midgestation. METHODS We reviewed all fetuses with cardiac asymmetry at echocardiograms performed at 18-22 weeks of gestation from 2006 to 2013. The data collected included the gestational age at(More)
OBJECTIVES The aim of this systematic review was to compare the postnatal outcomes, genetic testing results, and sonographic findings in 3 subtypes of tetralogy of Fallot. METHODS Thirty-six articles from the MEDLINE and EMBASE databases were selected for this review. The postnatal outcomes, karyotyping results, and sonographic findings of fetal tetralogy(More)