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Assessment of immunotoxicity of dibutyl phthalate using live zebrafish embryos.
A Zebrafish Thrombosis Model for Assessing Antithrombotic Drugs.
The larval zebrafish thrombosis model developed and validated in this study could be used for in vivo thromBosis studies and for rapid screening and efficacy assessment of antithrombotic drugs.
Tween‐80 and impurity induce anaphylactoid reaction in zebrafish
- Ruifeng Yang, Qiaocong Lao, Chun-Qi Li
- Biology, ChemistryJournal of applied toxicology : JAT
- 1 March 2015
High‐throughput zebrafish tryptase assay developed in this report could be used for assessing safety of Tween‐80‐containing injectable medicines and potentially for screening novel mast cell‐modulating drugs.
Sensitization and synergistic anti-cancer effects of Furanodiene identified in zebrafish models
Furanodiene showed a markedly synergistic anti-cancer effect when used in combination with 5-FU (5-Fluorouracil) for both human breast cancer MDA-MB-231 cells and human liver cancer BEL-7402 cells xenotransplanted into zebrafish.
A VEGFR1 antagonistic peptide inhibits tumor growth and metastasis through VEGFR1-PI3K-AKT signaling pathway inhibition.
This study demonstrated that monomeric peptide F56 had a significant anti-tumor activity by inhibiting angiogenesis, and laid the foundation for its clinical application.
Component-based biocompatibility and safety evaluation of polysorbate 80
In vitro and in vivo studies revealed that polyoxyethylene sorbitan dioleate (PSD) could induce the highest hemolysis rate, highest cytotoxicity to LO2 cells and highest fatality rate of zebrafish in spite of its relatively low content in polysorbate 80.
6′-O-Caffeoylarbutin inhibits melanogenesis in zebrafish
The result suggested that 6′-O-caffeoylarbutin could be a candidate natural product to serve as a skin-whitening ingredient with the merits of potent melanin inhibition, less toxicity and reversible melanin synthesis after stopping use.
Corrigendum to "Assessment of immunotoxicity of dibutyl phthalate using live zebrafish" [Fish & Shellfish Immunology (Fish & Shellfish Immunol.) 45 (2) (2015) 286-292].