Qianqian Wang

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In this work, we report the engineering of polyelectrolyte polymers coated Gold nanorods (AuNRs)-based nanocarriers that are capable of co-delivering small interfering RNA (siRNA) and an anticancer drug doxorubicin (DOX) to Panc-1 cancer cells for combination of both chemo- and siRNA-mediated mutant K-Ras gene silencing therapy. Superior anticancer efficacy(More)
Hip models that incorporate the biphasic behaviour of articular cartilage can improve understanding of the joint function, pathology of joint degeneration and effect of potential interventions. The aim of this study was to develop a specimen-specific biphasic finite element model of a porcine acetabulum incorporating a biphasic representation of the(More)
ACKNOWLEDGEMENTS First of all, I must express my utmost gratitude to my advisor, Dr. Mary Jean Harrold, for her unlimited support. Mary Jean helped me in all aspects of research from finding a research topic to writing a good research paper. Also, she gave me advice to be a good researcher as well as a good person. I am deeply indebted to Dr. Richard Vuduc.(More)
Software debugging is tedious and time consuming. To reduce the manual effort needed for debugging, researchers have proposed a considerable number of techniques to automate the process of fault localization; in particular, techniques based on information retrieval (IR) have drawn increased attention in recent years. Although reportedly effective, these(More)
BACKGROUND Epidemiologic studies have reported conflicting results relating smoking to suicide risk. We conducted a meta-analysis of prospective cohort studies to evaluate the association of cigarette smoking with completed suicide. METHODS Eligible prospective cohort studies were identified from PubMed and EMbase databases (from 1966 to May 2011) and the(More)
BACKGROUND Enteric viruses are a major cause of diarrhea in children, especially those <5 years old. Identifying the viral agents is critical to the development of effective preventive measures. This study aimed to determine the prevalence of common enteric viruses in children <5 years old presented with diarrhea to the Children's Hospital of Chongqing(More)
A geometric model has been developed for analyzing observed Beaufort/Chukchi Sea temperature and salinity profiles based on their geometric features. It contains four major components: (a) a nonhomogeneous mesh difference scheme for second derivatives ‫ץ‬ 2 T(z k)/‫ץ‬z 2 and ‫ץ‬ 2 S(z k)/‫ץ‬z 2 at each data point (z k , T k , S k); (b) a set of key depths(More)
1 Preprocessing Take account of that most tags are keyword rich and indicate the topic of tweets directly, but there was no space between two words. So Word Segmentation was used to separate the tags by space. This time we used the former max matching algorithm. The problem is that no dictionary is appropriate. Common words dictionary is partial and Oxford(More)