Qianqian Wang

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In this work, we report the engineering of polyelectrolyte polymers coated Gold nanorods (AuNRs)-based nanocarriers that are capable of co-delivering small interfering RNA (siRNA) and an anticancer drug doxorubicin (DOX) to Panc-1 cancer cells for combination of both chemo- and siRNA-mediated mutant K-Ras gene silencing therapy. Superior anticancer efficacy(More)
Hip models that incorporate the biphasic behaviour of articular cartilage can improve understanding of the joint function, pathology of joint degeneration and effect of potential interventions. The aim of this study was to develop a specimen-specific biphasic finite element model of a porcine acetabulum incorporating a biphasic representation of the(More)
BACKGROUND Epidemiologic studies have reported conflicting results relating smoking to suicide risk. We conducted a meta-analysis of prospective cohort studies to evaluate the association of cigarette smoking with completed suicide. METHODS Eligible prospective cohort studies were identified from PubMed and EMbase databases (from 1966 to May 2011) and the(More)
BACKGROUND Cell-free microRNAs stably and abundantly exist in body fluids and emerging evidence suggests cell-free microRNAs as novel and non-invasive disease biomarker. Deregulation of miR-29 is involved in the pathogenesis of diabetic nephropathy and insulin resistance thus may be implicated in diabetic vascular complication. Therefore, we investigated(More)
Software debugging is tedious and time consuming. To reduce the manual effort needed for debugging, researchers have proposed a considerable number of techniques to automate the process of fault localization; in particular, techniques based on information retrieval (IR) have drawn increased attention in recent years. Although reportedly effective, these(More)
BACKGROUND AND AIMS MET, the hepatocyte growth factor receptor, is a receptor tyrosine kinase overexpressed and activated in a subset of gastric cancer. Several studies investigated the relationship between MET amplification and expression with the clinical outcome in patients with gastric cancer, but yielded conflicting results. We performed a systematic(More)
In this paper, we proposed an effective method which can recognize dynamic hand gesture by analyzing the information of motion trajectory captured by leap motion in three-dimension space. A simple gesture spotting is tried. And the orientation characteristics are quantified and coded as the feature after pre-processing the data. Then an improved discrete(More)
BACKGROUND Enteric viruses are a major cause of diarrhea in children, especially those <5 years old. Identifying the viral agents is critical to the development of effective preventive measures. This study aimed to determine the prevalence of common enteric viruses in children <5 years old presented with diarrhea to the Children's Hospital of Chongqing(More)