Qiang-yi Wang

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BACKGROUND High genetic variability at reverse transcriptase (RT) region of hepatitis B virus (HBV) could confer resistance to nucleos(t)ide analogues (NUCs). The aim of this study was to identify new RT amino acid (AA) substitutions related to NUCs resistance. METHODS HBV RT sequences of genotype C from 501 chronic hepatitis B (CHB) patients were(More)
OBJECTIVE To investigate the health effects of 1-bromopropane (1-BP) on female exposed workers. METHODS Four 1-BP manufacturing plants were investigated. Workers were interviewed with questionnaire and examined with neurobehavioral core test battery, nerve conduction velocity tests of nervus tibialis and nervus suralis, vibration sensation test,(More)
OBJECTIVE To explore the dose-effect relationship between 1-bromopropane (1-BP) exposure and health effects in workers. METHODS Occupational field investigations were conducted in 1-BP factories. Ambient 1-BP concentrations were detected with detection tube, and the 8 h time-weighted average individual exposure levels (TWA-8 h) were measured by passive(More)
OBJECTIVE To compare the urinary 1-hydroxypyrene (1-OHP) concentrations between coke oven workers and non-occupational exposed individuals and to investigate the possible impact factors. METHODS Spot end-of-shift urine samples were collected in 265 coke oven workers and spot morning urine samples in 226 non-occupational exposed individuals. External(More)
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