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AβPP-selective BACE inhibitors (ASBI): novel class of therapeutic agents for alzheimer's disease.
A systematic approach was used to identify AβPP-selective BACE inhibitors (ASBI) and to evaluate their in vivo ability to modulate AβPP processing selectively. We identified a bioflavonoidExpand
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Four Decades of Research in Alzheimer's Disease (1975-2014): A Bibliometric and Scientometric Analysis.
BACKGROUND Bibliometric and scientometric methods can be applied to the study of a research field. OBJECTIVE We hypothesized that a bibliometric and scientometric analysis of the Alzheimer'sExpand
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COVID‐19 case fatality and Parkinson’s disease
Case fatality rates (CFR) of the novel coronavirus disease 2019 (COVID-19) have been reported ranging from 0% to 40% among patients with Parkinson’s disease (PD). However, because of small sampleExpand
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P3-016 SORBS2, SH3RF3, AND NPHP1 MODIFYAGE AT ONSET IN CARRIERS OF THE G206A MUTATION IN PSEN1 WITH FAMILIAL ALZHEIMER’S DISEASE
Background: Anxiety disorders affect 18% of Americans, and their managements remain to be a great challenge for the society. Aside from the anxiety disorders, there are many diseases, includingExpand
Approach to Cognitive Impairment in Parkinson's Disease.
Cognitive dysfunction is common in Parkinson's disease (PD) and predicts poor clinical outcomes. It is associated primarily with pathologic involvement of basal forebrain cholinergic and prefrontalExpand
Research progress on the genetic mutations in Alzheimer's disease and Parkinson's disease
With the rapid development of medical technology, the precision medicine appears. The accurate analysis of the genetic mutations provides the accuracy of diseasesis prediction diagnosis and targetedExpand