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The Consequences of technostress for end users in organizations: Conceptual development and empirical validation" (2008). T he research reported in this paper studies the phenomenon of technostress, that is, stress experienced by end users of Information and Communication Technologies (ICTs), and examines its influence on their job satisfaction, commitment(More)
Our recent work has addressed how and why software systems evolve over time, with a particular emphasis on software architecture and open source software systems [2, 3, 6]. In this position paper, we present a short summary of two recent projects.First, we have performed a case study on the evolution of the Linux kernel [3], as well as some other open(More)
Explanation of a process of development must ultimately be couched in the terms of the genomic regulatory code. Specification of an embryonic cell lineage is driven by a network of interactions among genes encoding transcription factors. Here, we present the gene regulatory network (GRN) that directs the specification of the skeletogenic micromere lineage(More)
A comprehensive transcriptome analysis has been performed on protein-coding RNAs of Strongylocentrotus purpuratus, including 10 different embryonic stages, six feeding larval and metamorphosed juvenile stages, and six adult tissues. In this study, we pooled the transcriptomes from all of these sources and focused on the insights they provide for gene(More)
Monideepa Tarafdar is an associate professor of information, operations, and technology management at the university of Toledo. She has an undergraduate degree in physics and a graduate degree in telecommunications and electronics engineering from the university of Calcutta, India. her ph.D. is in management from the Indian Institute of Management,(More)
Transcription factors of the Forkhead (Fox) family have been identified in many metazoans, and play important roles in diverse biological processes. Here we define the set of fox genes present in the sea urchin genome, and survey their usage during development. This genome includes 22 fox genes, only three of which were previously known. Of the 23 fox gene(More)
We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with(More)