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OBJECTIVE To compare the clinical outcomes between thulium laser transurethral enucleation of the prostate (ThuLEP) (70 W) and holmium laser transurethral enucleation of the prostate (HoLEP) (90 W) in a prospective randomized trial with 18 months of follow-up. Both ThuLEP and HoLEP effectively relieve the obstructive symptoms due to benign prostatic(More)
OBJECTIVE To investigate and compare the effect and safety of Holmium laser and Thulium laser in transurethral enucleation of the prostate in BPH patients. METHODS Ninety-eight BPH patients were divided into 2 groups and underwent transurethral enucleation of the prostate with holmium laser (Ho group) and thulium laser (Th group) respectively. Comparisons(More)
Genome-wide association studies have identified 13 single nucleotide polymorphisms (SNPs) that are associated with bladder cancer; three of these SNPs were validated in the Chinese population. This study assessed the performance of these three SNPs, in combination, to predict genetic susceptibility to bladder cancer in Chinese. Three previously established(More)
Prostate cancer risk–associated variants have been reported in populations of European descent, African-Americans and Japanese using genome-wide association studies (GWAS). To systematically investigate prostate cancer risk–associated variants in Chinese men, we performed the first GWAS in Han Chinese. In addition to confirming several associations reported(More)
In this paper, we apply an enhanced sampling method introduced earlier to study the folding mechanism of a beta-hairpin, trpzip2, using an all-atom potential for the protein and an implicit model for the solvent. The enhanced sampling method allows us to obtain multiple protein folding and unfolding trajectories in relatively short simulations. The(More)
Despite the critical role of microRNA in inflammatory response, little is known about its function in inflammation-induced Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS). To investigate the potential role of microRNA146a (miR-146a) in ALI, we used lipopolysaccharide (LPS)-induced ALI rat model. Our data revealed that LPS-induced lung(More)
A combined simulation and experimental study was performed to investigate how methanol affects the structure of a model peptide BBA5. BBA5 forms a stable β-hairpin-α-helix structure in aqueous solutions. Molecular dynamics simulations were performed in water and methanol/water solutions using all-atom explicit models. NMR experiments were used to test the(More)
To distinguish chatter gestation, chatter recognition method based on hybrid PCA(Principal Compenent Analysis) and SVM(Support Vector Machine) is proposed for dynamic patterns of chatter gestation in cutting process. At first, FFT features are extracted from the vibration signal of cutting process, then FFT vectors are presorted and introduced to PCA-SVM(More)
As an indispensable and time-consuming component in JPEG2000, lifting-based 2D DWT is often implemented with a dedicated hardware in systems which require realtime processing. However, most of the proposed architectures for 2D DWT failed to achieve high performance since they didn't fully exploit the potential parallelisms within the algorithm. In this(More)
In edge envelope process of milling cutter CAD/CAM, the grinding depth is variable which causes grinding force to change on a large scale and the error of edge envelope to increase. To improve form cutter accuracy, a closed-loop control system was designed to accomplish control of envelope process. For complicated dynamic process, fuzzy controller was used(More)