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Efflux of monocaroxylates like lactate, pyruvate, and ketone bodies from astrocytes through monocarboxylate transporter 4 (MCT4) supplies the local neuron population with metabolic intermediates to meet energy requirements under conditions of increased demand. Disruption of this astroglial-neuron metabolic coupling pathway may contribute to epileptogenesis.(More)
There are two statistical decision making questions regarding statistically detecting sings of denial-of-service flooding attacks. One is how to represent the distributions of detection probability, false alarm probability and miss probability. The other is how to quantitatively express a decision region within which one may make a decision that has high(More)
Visual exploration of volume data often requires the user to manipulate the orientation and position of a slicing plane in order to observe, annotate or measure its internal structures. Such operations, with its many degrees of freedom in 3D space, map poorly into interaction modalities afforded by mouse-keyboard interfaces or flat multi-touch displays(More)
Urokinase-type plasminogen activator receptor (uPAR) is a glycosyl phosphatidylinositol-anchored protein involved in cell adhesion, proliferation, differentiation, migration, invasion, and tissue repair and remodeling. Our aim was to investigate uPAR expression in the frontal cortex of patients with intractable frontal lobe epilepsy and to explore the(More)
Investigating the hepatoprotective effect of calycosin against acute liver injury in association with FXR activation and STAT3 phosphorylation. The acute liver injury model was established by intraperitoneal injection of CCl4 in C57BL/6 mice. Serum alanine aminotransferase, aspartate aminotransferase, HE staining and TUNEL assay were used to identify the(More)
A VR-based simulator helps trainees develop skills for catheterization, a fundamental but difficult procedure in vascular interventional radiology. A deformable model simulates the complicated behavior of guide wires and catheters, using the principle of minimum total potential energy. A fast, stable multigrid solver ensures realistic simulation and(More)