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Recent genome-wide association studies have identified 14 genetic variants associated with bladder cancer in Caucasians. The effects of these risk variants and their cumulative effects in Asian populations are unknown. We genotyped these newly identified variants in a case-control study of 1,050 patients diagnosed with bladder cancer and 1,404 controls in(More)
To predict protein structure based on HydrophobicPolar model(HP model) in two-dimensional space is called 2D HP protein folding problem. Ant Colony Optimization(ACO), which is inspired by the foraging behavior of ants, is a popular heuristic approach for solving combinatorial optimization problems. This paper presents a method of solving the 2D HP protein(More)
BACKGROUND Warm ischemic injury is one of the most important factors affecting renal function in partial nephrectomy (PN). The technique of segmental renal artery clamping emerges as an alternative to conventional renal artery clamping for renal hilar control. OBJECTIVE To evaluate the feasibility and efficiency of laparoscopic PN (LPN) with segmental(More)
Small auxin-up RNA (SAUR) gene family is large, and the members of which can be rapidly induced by auxin and encode highly unstable mRNAs. SAUR genes are involved in various developmental and physiological processes, such as leaf senescence, fruitlet abscission, and hypocotyl development. However, their modes of action in citrus remain unknown. Hereby, a(More)
BACKGROUND MicroRNAs (miRNAs) are a class of small non-coding RNAs to regulate cell differentiation, proliferation, development, and apoptosis. The single nucleotide polymorphism (SNP) rs895819 is located at the terminal loop of pre-miR-27a. Here, we aimed to investigate whether SNP rs895819 was associated with the development of renal cell cancer (RCC) in(More)
MicroRNAs (miRNAs) play a critical role in post-transcriptional gene regulation and have been shown to control many genes involved in various biological and metabolic processes. This work investigated miRNAs in rice (Oryza sativa), an important food crop. High-throughput sequencing technology was used to reveal expression differences in miRNAs between(More)
BACKGROUND Studies comparing coronary artery bypass grafting (CABG) with drug-eluting stent (DES) for the treatment of diabetic patients with multivessel disease are relatively scarce although controversies exist concerning the relative efficacy of CABG versus DES. HYPOTHESIS The aim of this study was to evaluate the effect of drug-eluting stent (DES)(More)
MOTIVATION Mutations in human genome are mainly through single nucleotide polymorphism, some of which can affect stability and function of proteins, causing human diseases. Several methods have been proposed to predict the effect of mutations on protein stability; but most require features from experimental structure. Given the fast progress in protein(More)
In this paper, a post digital linearization technique is proposed and demonstrated for a conventional intensity-modulation direct-detection analog photonic link. Instead of precisely emulating the transfer function of the whole nonlinear system in the digital domain, the key distortion information is directly acquired from hardware. By low biasing the(More)
Automation in cooperative editing is of use for it relieves human work. Access control in cooperative editing with workflow (CEWW) is important but hard to achieve. A novel access control model, activity based cooperative editing access control (ACEAC), is set up for CEWW, which is a dynamic, active, adaptive and context sensitive model. A fine-grained and(More)