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Ion channels are a large superfamily of membrane proteins that pass ions across membranes. They are critical to diverse physiological functions in both excitable and nonexcitable cells and underlie many diseases. As a result, they are an important target class which is proven to be highly "druggable". However, for high throughput screening (HTS), ion(More)
Lü Q., Tang M.-j., Cai j.-r., Zhao j.-w., Vittayapadung S. (2011): Vis/NIR hyperspectral imaging for detection of hidden bruises on kiwifruits. Czech j. Food Sci., 29: 595–602. It is necessary to develop a non-destructive technique for kiwifruit quality analysis because the machine injury could lower the quality of fruit and incur economic losses. Bruises(More)
BACKGROUND People with metabolic syndrome are at higher risk for developing coronary artery disease (CAD). The effect of the metabolic syndrome on outcomes in patients with preexisting CAD has not been well studied. This study was conducted to assess the prevalence, characteristics, in hospital and long term prognosis of CAD with metabolic syndrome and to(More)
Henoch–Schönlein purpura (HSP) is the most common systemic vasculitis of childhood. The molecular etiology of HSP is not well understood. The purpose of this study is to investigate the association between polymorphisms in C1GALT1 gene and the risk of HSP in a Chinese population. A total of unrelated 542 northern Chinese were enrolled in this study.(More)
OBJECTIVE To evaluate the technique and clinical outcomes of modified transperitoneal laparoscopic radical prostatectomy. METHODS A total of 105 patients received the operation with age ranging from 51 to 73 years from January 2008 to June 2010. Mean level of serum prostate specific antigen was 13.6 µg/L and mean prostatic volume was 45 ml. Pathological(More)
To simplify the prediction model of kiwifruit firmness, SNV was used to preprocess the near infrared (NIR) spectra (1 000-2 500 nm)of kiwifruit. PLS model simplification by optimizing spectral intervals and decreasing the number of factors through net analyte preprocessing (NAP)was carried out. Results showed that the performance of NAP/PLS model is the(More)
BACKGROUND The optimal revascularization strategy in patients with heart failure with preserved ejection fraction (HFPEF) remains unclear. The aim of the present study was to compare the effects of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in patients with HFPEF. METHODS From July 2003 through September 2005, a(More)
OBJECTIVE To explore the effect of early statin therapy (atorvastatin and simvastatin) on mortality in patients with non-ischemic dilated cardiomyopathy. METHODS A retrospective study was conducted at a single center. A total of 315 patients with non-ischemic dilated cardiomyopathy, admitted into our hospital from January 2002 to December 2008, were(More)
BACKGROUND C-reactive protein (CRP) is a lowly expressed marker for inflammatory response. This study aimed to evaluate the prognostic value of baseline CRP levels in patients undergoing coronary revascularization in the context of modern medical treatment. METHODS This was a retrospective study in a single center. Four hundred and fourteen patients were(More)
OBJECTIVE To evaluate the prevalence of unrecognized diabetes in patients with coronary heart disease, the control of the risk factors of CHD, and the long-term prognosis of these patients. METHODS The clinical data of CHD patients with complete data, including clinical characters, target organ damage, percentage of controlled risk factors, and clinical(More)