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Two new nortriterpenoid saponins from Salicornia bigelovii Torr. and their cytotoxic activity.
Two new 30-nortriterpenoid glycosides are isolated for the first time from Chenopodiaceae and showed moderate activity against four cell lines, HL-60 (promyelocytic leukemia), MCF-7 (breast carcinoma), HepG2 (liver carcinoma) and A549 (lung carcinoma). Expand
Inhibition of COX-2 and PGE2 in LPS-stimulated RAW264.7 cells by lonimacranthoide VI, a chlorogenic acid ester saponin.
Results indicate that lonimacranthoide VI is an important anti-inflammatory constituent of Lonicera macranthOides and that the anti- inflammatory effect is attributed to the inhibition of PGE2 production through COX activity and mRNA expression. Expand
[Overview of current researches on Tibetan medicine "zuotai"].
The paper reviewed the resent progress of the study about "Zuotai" in chemical composition, pharmacodynamics and pharmacokinetics, toxicology and clinical application, and established the basis for further study. Expand
[Studies on the chemical constituents of Evodia rutaecarpa (Juss.) Benth].
Compound 1 is a new alkaloid named evodianinine, found in Evodia rutaecarpa, and it is confirmed that this substance has new physico-chemical properties. Expand
A New Alkaloid from the Herb of Corydalis saxicola
Abstract Aim To study the chemical constituents of the herb of Corydalis saxicola Bunting. Methods Silica gel column chromatography and Sephadex LH-20 were used to isolate the compounds, andExpand
Induction of apoptosis by Bigelovii A through inhibition of NF-κB activity
Bigelovii A significantly inhibited the proliferation of human breast cancer cells in a concentration-dependent manner and downregulated the constitutive activation of nuclear factor (NF)-κB, as indicated by the electrophoretic mobility gel shift assay and immunocytochemistry. Expand
In vitro antioxidant activity of Polysaccharide from Sedum aizoon L. extracts
Crude polysaccharide was isolated from the stem of Sedum aizoon L. Antioxidant activity of crude polysaccharide was evaluated with 2, 20-diphenyl-l-picrylhydrazyl (DPPH), 2,Expand
Three new quinazolines from Evodia rutaecarpa and their biological activity.
Three new quinazoline alkaloids were isolated from the MeOH extract of E. rutaecarpa, and rhetsinine (8) showed potential as a pesticide and exhibited excellent inhibition against Xanthomonas oryzae pv. Expand
Macranthoside B Induces Apoptosis and Autophagy Via Reactive Oxygen Species Accumulation in Human Ovarian Cancer A2780 Cells
The ROS/AMPK/mTOR pathway mediates the effect of MB on induction of apoptosis via autophagy in human ovarian carcinoma cells. Expand
Triterpenoids from the Herbs of Salicornia bigelovii
A new nortriterpene saponin, 3-O-β-d-glucuronopyranosyl-30-norolean-12,20(29)-dien-23-oxo-28-oic acid, namely bigelovii D (11), was isolated from the hydroalcoholic extract of herbs of Salicornia bigelOVii along with 10 known saponins and showed potent antifungal activities in vitro. Expand