Forkhead box protein 3 (Foxp3) is known as a specific marker for regulatory T cells which contribute to immunosuppression in tumor microenvironment. However, existing studies regarding clinical significance of Foxp3+ tumor-infiltrating lymphocytes (TILs) in glioblastoma (GBM) remained discrepant. In this study, we aimed to explore whether this subtype of… (More)
Tripartite motif (TRIM) proteins are involved in tumorigenesis. Here, we examined the expression, biological function, and clinical significance of tripartite motif containing 28 (TRIM28) in glioma, a locally aggressive brain tumor. First, TRIM28 expression was significantly higher in glioma (n = 138) than in non-glioma controls (n = 6). TRIM28 expression… (More)
Data mining is playing a vital role in various application fields. One important issue in data mining is clustering, which is a process of grouping data with high similarity. Density-based clustering is an effective method that can find clusters in arbitrary shapes in feature space, and DBSCAN (Density-Based Algorithm for Discovering Clusters in Large… (More)
An unsymmetric tetracarboxylic ligand collaborates with 4,4'-bipyridine to induce spontaneous resolution to form homochiral 3D coordination frameworks, while the use of longer dipyridyl ligands instead of 4,4'-bipyridine leads to isoreticular but heterochiral frameworks.
OBJECTIVE The optimal treatment for aneurysmal subarachnoid hemorrhage (SAH) in elderly patients is controversial. Focusing on this specific population, we analyzed early outcomes after endovascular or neurosurgical treatment and developed a prognostic model to aid in clinical decision-making processes. METHODS SAH patients aged 60 years or older who… (More)
BACKGROUND Clipping and bypass surgery are common therapeutic options for the management of giant internal carotid artery (ICA) aneurysms. However, potential ischemic risks may be exaggerated by prolonged temporary occlusion (PTO) during the surgery. Monitoring motor-evoked potentials (MEPs) is a sensitive technique for detecting potential ischemia… (More)