Physiological/behavioral/perceptual responses to an auditory stimulus can be inhibited by another leading auditory stimulus at certain stimulus intervals, and have been considered useful models of auditory gating processes. Two typical examples of auditory gating are prepulse inhibition of the startle reflex and the precedence effect (echo suppression).… (More)
Most animal vocalizations, including echolocation signals used by bats, contain frequency-modulated (FM) components. Previous studies have described a class of neurons in the inferior colliculus (IC) of the big brown bat that respond exclusively to sinusoidally frequency modulated (SFM) signals and fail to respond to pure tones, noise, amplitude-modulated… (More)
Forkhead box protein 3 (Foxp3) is known as a specific marker for regulatory T cells which contribute to immunosuppression in tumor microenvironment. However, existing studies regarding clinical significance of Foxp3+ tumor-infiltrating lymphocytes (TILs) in glioblastoma (GBM) remained discrepant. In this study, we aimed to explore whether this subtype of… (More)
Tripartite motif (TRIM) proteins are involved in tumorigenesis. Here, we examined the expression, biological function, and clinical significance of tripartite motif containing 28 (TRIM28) in glioma, a locally aggressive brain tumor. First, TRIM28 expression was significantly higher in glioma (n = 138) than in non-glioma controls (n = 6). TRIM28 expression… (More)
Data mining is playing a vital role in various application fields. One important issue in data mining is clustering, which is a process of grouping data with high similarity. Density-based clustering is an effective method that can find clusters in arbitrary shapes in feature space, and DBSCAN (Density-Based Algorithm for Discovering Clusters in Large… (More)
An unsymmetric tetracarboxylic ligand collaborates with 4,4'-bipyridine to induce spontaneous resolution to form homochiral 3D coordination frameworks, while the use of longer dipyridyl ligands instead of 4,4'-bipyridine leads to isoreticular but heterochiral frameworks.