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PURPOSE To study subfoveal choroidal thickness (SFCT) in adult Chinese subjects and its correlation with ocular biometric parameters, refractive error, and age. DESIGN Population-based longitudinal study. PARTICIPANTS The population-based Beijing Eye Study 2011 included 3468 individuals with a mean age of 64.6±9.8 years (range, 50-93 years). METHODS A(More)
OBJECTIVE To evaluate the prevalence of age-related maculopathy (ARM) in adult Chinese living in rural or urban regions of mainland China. DESIGN Population-based prevalence study. METHODS The study included 4439 subjects (aged 40 or more years) out of 5324 subjects invited to participate (response rate 83.4%). It was held in rural and urban regions of(More)
OBJECTIVE To assess the 10-year incidence of retinal vein occlusions (RVOs) and associated factors in adult Chinese subjects. DESIGN Population-based, longitudinal study. PARTICIPANTS The Beijing Eye Study, which included 4439 subjects (age: 40+ years) in 2001, was repeated in 2011 with 2695 subjects participating (66.4% of the survivors). METHODS The(More)
OBJECTIVE To determine whether mesenchymal stem cells (MSCs) can be isolated in third-trimester amniotic fluid (AF) and their differentiation induced. METHOD Sufficient numbers of MSCs were isolated from the AF of 15 healthy women undergoing cesarean delivery in the third trimester to be cultured and induced to differentiate into osteocytes. RESULTS(More)
PURPOSE To determine the prevalence and progression of myopic retinopathy in Chinese adults. DESIGN Population-based cross-sectional study. PARTICIPANTS The Beijing Eye Study 2001 included 4439 subjects of 5324 individuals who were invited to participate (response rate, 83.4%); the eligibility criterion was an age of 40+ years. The study was repeated in(More)
JASMONATE ZIM-domain (JAZ) proteins play important roles in plant defence and growth by regulating jasmonate signalling. Through data mining, we discovered that the JAZ7 gene was up-regulated in darkness. In the dark, the jaz7 mutant displayed more severe leaf yellowing, quicker chlorophyll degradation, and higher hydrogen peroxide accumulation compared(More)
PURPOSE To evaluate prevalence and associated factors for myopia in high school students in Beijing. METHODS Grade 10 and 11 high school students were randomly selected from nine randomly selected districts of Beijing. The students underwent non-cylcoplegic auto-refractometry and an interview. RESULTS Out of 4798 eligible students, 4677 (93.4%) students(More)
PURPOSE To assess factors associated with myopia in school children in rural and urban parts of Greater Beijing. METHODS The Beijing Pedriatic Eye Study was a population-based cross-sectional study, in which one school of each level (primary, junior high, senior high) was randomly selected from nine randomly selected districts out of 18 districts of(More)
PURPOSE To assess the relationship of hypertension with major eye diseases and other ocular parameters. DESIGN Population-based study. PARTICIPANTS The Beijing Eye Study is a population-based study that included 4439 Chinese subjects examined at the baseline examination in 2001; there was a follow-up examination in 2006, in which 3251 subjects(More)
BACKGROUND There is an increasing interest in the role of astrocytes contributing to the intrinsic bioremediation of ischemic brain injury. The purpose of this study was to disclose the effects and mechanism of midazolam (MDZ) on the proliferation and apoptosis of astrocytes under oxygen glucose deprivation (OGD) condition. METHODS The astrocytes were(More)