Learn More
We present a novel approach to address the representation issue and the matching issue in face recognition (verification). Firstly, our approach encodes the micro-structures of the face by a new learning-based encoding method. Unlike many previous manually designed encoding methods (e.g., LBP or SIFT), we use unsupervised learning techniques to learn an(More)
Face representation is a crucial step of face recognition systems. An optimal face representation should be discriminative, robust, compact, and very easy-to-implement. While numerous hand-crafted and learning-based representations have been proposed, considerable room for improvement is still present. In this paper, we present a very easy-to-implement deep(More)
We present a new approach to localize extensive facial landmarks with a coarse-to-fine convolutional network cascade. Deep convolutional neural networks (DCNN) have been successfully utilized in facial landmark localization for two-fold advantages: 1) geometric constraints among facial points are implicitly utilized, 2) huge amount of training data can be(More)
Eye contact plays a crucial role in our everyday social interactions. The ability of a device to reliably detect when a person is looking at it can lead to powerful human-object interfaces. Today, most gaze-based interactive systems rely on gaze tracking technology. Unfortunately, current gaze tracking techniques require active infrared illumination,(More)
Intracellular bacteria have been shown to cause autophagy, which impacts infectious outcomes, whereas extracellular bacteria have not been reported to activate autophagy. Here, we demonstrate that Pseudomonas aeruginosa, a Gram-negative extracellular bacterium, activates autophagy with considerably increased LC3 punctation in both an alveolar macrophage(More)
Spermatogonial stem cells (SSCs) can produce numerous male gametes after transplantation into recipient testes, presenting a valuable approach for gene therapy and continuous production of gene-modified animals. However, successful genetic manipulation of SSCs has been limited, partially due to complexity and low efficiency of currently available genetic(More)
The successful treatment of central nervous system (CNS) disorders is hampered by inefficient drug delivery across the blood-brain barrier (BBB). Transferrin (Tf) could facilitate the transcytosis of coupled nanocarriers through Tf receptor (TfR) mediated pathway. In this study, Tf-modified paclitaxel-loaded polyphosphoester hybrid micells (TPM) was(More)
The effective chemotherapy for glioblastoma multiform (GBM) requires a nanomedicine that can both penetrate the blood-brain barrier (BBB) and target the glioma cells subsequently. In this study, Transferrin (Tf) modified cyclo-[Arg-Gly-Asp-d-Phe-Lys] (c[RGDfK])-paclitaxel conjugate (RP) loaded micelle (TRPM) was prepared and evaluated for its targeting(More)
This randomized controlled trial compares 2 mobilization regimens after shoulder hemiarthroplasty for acute 3- and 4-part fractures. The aim was to establish whether the length of immobilization plays a role in the functional outcome, tuberosity healing, and subsequent range of motion. The same prosthesis and surgical technique were used. We recruited 59(More)