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O-GlcNAc is a monosaccharide attached to serine or threonine hydroxyl moieties on numerous nuclear and cytoplasmic proteins; O-GlcNAcylation is dynamically regulated by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). Although recent studies have shown that O-GlcNAcylation plays essential roles in breast cancer progression, it is also necessary to know(More)
Breast cancer has been the most common malignant tumor among women in many large cities of China. The aim of this study was to clarify the prognostic significance of serum anti-p53 antibodies (p53 Abs) in Chinese patients of breast cancer. One hundred and forty-four patients with invasive ductal carcinoma of breast were involved in this study. The(More)
OBJECTIVE To study the prevalence of thyroid diseases, as well as characteristics of the disease spectrum and thyroid autoimmunity in women at the end of pregnancy. METHODS Six hundred and sixty-four pregnant women (pregnancy group) and 276 non-pregnant women (control group) were enrolled in the study. Serum thyrotropin (TSH), thyroid peroxidase antibody(More)
Recently, the focus of IT outsourcing has been shifting from the “what” and “why” issues to “how” companies manage outsourcing process, during which the relationship management becomes vitally important for the overall success of IT outsourcing. Simultaneously, trust, as a component of relationship, plays a central role in the success of IT outsourcing(More)
In spite of the continuous increase in IT outsourcing activities globally, a major percentage of outsourcing deals failed or suffered from serious problems. In China regions where IT outsourcing practice is still at its initial stage, the situation is even serious: there lacks systematic guidance in terms of how to negotiate decent contracts and how to(More)
OBJECTIVE To investigate the dynamic changes of serum Th1 and Th2 cytokines in patients with postpartum thyroiditis (PPT) during the first postpartum year. METHODS 21 patients diagnosed as clinical PPT and 11 healthy postpartum women were enrolled in the study. Blood samples were taken before delivery and every 3 months postpartum for testing serum(More)
3D audio effects can provide immersive auditory experience, but we often face the so-called in-head localization (IHL) problem in headphone sound reproduction. To address this problem, we propose an effective sound image externalization approach. Specifically, we consider several important factors related to sound propagation, which include image-source(More)
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