• Publications
  • Influence
Clinical findings in 111 cases of influenza A (H7N9) virus infection.
  • H. Gao, H. Lu, +39 authors L. Li
  • Medicine
  • The New England journal of medicine
  • 12 June 2013
BACKGROUND During the spring of 2013, a novel avian-origin influenza A (H7N9) virus emerged and spread among humans in China. Data were lacking on the clinical characteristics of the infectionsExpand
  • 544
  • 37
  • PDF
Twist1-Mediated Adriamycin-Induced Epithelial-Mesenchymal Transition Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells
  • Q. Li, J. Xu, +6 authors Z. Xu
  • Medicine, Biology
  • Clinical Cancer Research
  • 15 April 2009
Purpose: Besides its therapeutic effects, chemotherapeutic agents also enhance the malignancy of treated cancers in clinical situations. Recently, epithelial-mesenchymal transition (EMT) hasExpand
  • 284
  • 20
  • PDF
Upregulated MALAT-1 contributes to bladder cancer cell migration by inducing epithelial-to-mesenchymal transition.
Recent studies reveal that long non-coding RNAs (lncRNAs) have been shown to have important regulatory roles in cancer biology, and lncRNA MALAT-1 expression is upregulated in some tumors. However,Expand
  • 290
  • 17
cGAS is essential for cellular senescence
Significance Cellular senescence is important for the maintenance of tissue homeostasis. Dysregulation of senescence is linked to many human diseases, such as cancer, premature aging, and age-relatedExpand
  • 271
  • 17
  • PDF
Dock180 and ELMO1 Proteins Cooperate to Promote Evolutionarily Conserved Rac-dependent Cell Migration*
Cell migration is essential throughout embryonic and adult life. In numerous cell systems, the small GTPase Rac is required for lamellipodia formation at the leading edge and movement ability.Expand
  • 188
  • 17
IOT Gateway: BridgingWireless Sensor Networks into Internet of Things
In this paper, we proposed an IOT Gateway system based on Zigbee and GPRS protocols according to the typical IOT application scenarios and requirements from telecom operators, presented the data transmission between wireless sensor networks and mobile communication networks, protocol conversion of different sensor network protocols, and control functionalities for sensor networks. Expand
  • 349
  • 16
Particle-phase chemistry of secondary organic material: modeled compared to measured O:C and H:C elemental ratios provide constraints.
Chemical mechanisms for the production of secondary organic material (SOM) are developed in focused laboratory studies but widely used in the complex modeling context of the atmosphere. Given thisExpand
  • 135
  • 14
DUNet: A deformable network for retinal vessel segmentation
In this paper, we propose Deformable U-Net (DUNet), which exploits the retinal vessels’ local features with a U-shape architecture, in an end to end manner for retinal vessel segmentation. Expand
  • 82
  • 12
  • PDF
Supporting scientific discovery learning in a simulation environment
A systematic analysis of the internal conditions of scientific discovery learning to propose a triple scheme for learning support design that includes interpretative support (IS), experimental support (ES), and reflective support (RS). Expand
  • 149
  • 11
  • PDF
An e-whiteboard application to support early design-stage sketching of UML diagrams
We describe a Unified Modelling Language (UML) diagramming tool that uses an e-whiteboard, pen-based sketching interface to support collaborative design. Expand
  • 100
  • 9
  • PDF