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- Publications
- Influence
CmeABC Functions as a Multidrug Efflux System in Campylobacter jejuni
ABSTRACT Campylobacter jejuni, a gram-negative organism causing gastroenteritis in humans, is increasingly resistant to antibiotics. However, little is known about the drug efflux mechanisms in this… Expand
Antibiotic resistance in Campylobacter: emergence, transmission and persistence.
- Taradon Luangtongkum, Byeonghwa Jeon, J. Han, Paul Plummer, C. Logue, Q. Zhang
- Biology, Medicine
- Future microbiology
- 4 March 2009
Campylobacter is a leading foodborne bacterial pathogen, which causes gastroenteritis in humans. This pathogenic organism is increasingly resistant to antibiotics, especially fluoroquinolones and… Expand
CmeR Functions as a Transcriptional Repressor for the Multidrug Efflux Pump CmeABC in Campylobacter jejuni
- Jun Lin, M. Akiba, O. Şahin, Q. Zhang
- Biology, Medicine
- Antimicrobial Agents and Chemotherapy
- 1 March 2005
ABSTRACT CmeABC, a resistance-nodulation-division (RND) type of efflux pump, contributes to Campylobacter resistance to a broad spectrum of antimicrobial agents and is also essential for… Expand
Bile salts modulate expression of the CmeABC multidrug efflux pump in Campylobacter jejuni.
- Jun Lin, Cédric Cagliero, +4 authors Q. Zhang
- Biology, Medicine
- Journal of bacteriology
- 1 November 2005
CmeABC, a multidrug efflux pump, is involved in the resistance of Campylobacter jejuni to a broad spectrum of antimicrobial agents and is essential for Campylobacter colonization in animal intestine… Expand
Interaction of CmeABC and CmeDEF in conferring antimicrobial resistance and maintaining cell viability in Campylobacter jejuni.
- M. Akiba, Jun Lin, Yi-Wen Barton, Q. Zhang
- Biology, Medicine
- The Journal of antimicrobial chemotherapy
- 2006
OBJECTIVES
To determine the role of CmeDEF in conferring antimicrobial resistance in Campylobacter jejuni and examine the interaction of CmeABC and CmeDEF in mediating antimicrobial resistance and… Expand
Campylobacter colonization in poultry: sources of infection and modes of transmission
- O. Şahin, T. Y. Morishita, Q. Zhang
- Medicine, Biology
- Animal Health Research Reviews
- 1 December 2002
Abstract Since its recognition as a human pathogen in the early 1970s, Campylobacter jejuni has now emerged as the leading bacterial cause of food-borne gastroenteritis in developed countries.… Expand
Critical Role of Multidrug Efflux Pump CmeABC in Bile Resistance and In Vivo Colonization of Campylobacter jejuni
ABSTRACT CmeABC functions as a multidrug efflux pump contributing to the resistance of Campylobacter to a broad range of antimicrobials. In this study, we examined the role of CmeABC in bile… Expand
Effect of Campylobacter-Specific Maternal Antibodies on Campylobacter jejuni Colonization in Young Chickens
- O. Şahin, N. Luo, Shouxiong Huang, Q. Zhang
- Biology, Medicine
- Applied and Environmental Microbiology
- 1 September 2003
ABSTRACT Using laboratory challenge experiments, we examined whether Campylobacter-specific maternal antibody (MAB) plays a protective role in young chickens, which are usually free of Campylobacter… Expand
In Vivo Selection of Campylobacter Isolates with High Levels of Fluoroquinolone Resistance Associated with gyrA Mutations and the Function of the CmeABC Efflux Pump
- N. Luo, O. Şahin, Jun Lin, L. Michel, Q. Zhang
- Biology, Medicine
- Antimicrobial Agents and Chemotherapy
- 1 January 2003
ABSTRACT Enrofloxacin treatment of chickens infected with fluoroquinolone(FQ)-sensitive Campylobacter promoted the emergence of FQ-resistant Campylobacter mutants which propagated in the intestinal… Expand
Emergence of a Tetracycline-Resistant Campylobacter jejuni Clone Associated with Outbreaks of Ovine Abortion in the United States
- O. Şahin, P. Plummer, +7 authors Q. Zhang
- Biology, Medicine
- Journal of Clinical Microbiology
- 5 March 2008
ABSTRACT Campylobacter infection is one of the major causes of ovine abortions worldwide. Historically, Campylobacter fetus subsp. fetus was the major cause of Campylobacter-associated abortion in… Expand