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The Hepatitis B Virus X Protein Disrupts Innate Immunity by Downregulating Mitochondrial Antiviral Signaling Protein
Previous studies have shown that both hepatitis A virus and hepatitis C virus inhibit innate immunity by cleaving the mitochondrial antiviral signaling (MAVS) protein, an essential component of theExpand
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Gut microbiota and intestinal FXR mediate the clinical benefits of metformin
The anti-hyperglycemic effect of metformin is believed to be caused by its direct action on signaling processes in hepatocytes, leading to lower hepatic gluconeogenesis. Recently, metformin wasExpand
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Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters
Since metabolic process differs between humans and mice, studies were performed in hamsters, which are generally considered to be a more appropriate animal model for studies of obesity-relatedExpand
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Essential oil from Zanthoxylum bungeanum Maxim. and its main components used as transdermal penetration enhancers: a comparative study
  • Y. Lan, H. Li, +4 authors Q. Wu
  • Chemistry, Medicine
  • Journal of Zhejiang University SCIENCE B
  • 1 November 2014
Our previous studies had confirmed that the essential oil from Zanthoxylum bungeanum Maxim. (Z. bungeanum oil) could effectively enhance the percutaneous permeation of drug molecules as a naturalExpand
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Microbial mechanisms of using enhanced ecological floating beds for eutrophic water improvement.
Enhanced ecological floating beds were implemented to reduce nutrient quantity and improve the water quality of a eutrophic lake. The results showed that average removal efficiencies of CODCr, totalExpand
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Development of an Enzyme-linked Immuno-Sorbent Assay (ELISA) Method for Carbofuran Residues
The haptens 4-[[(2,3-dihydro-2,2-dimethyl-7-benzofuranyloxy)carbonyl]-amino]butanoic acid (BFNB) and 6-[((2,3-dihydro-2,2-dimethyl-7-benzofuranyloxy)-carbonylamino]hexanoic acid (BFNH) wereExpand
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Talin1 is required for cardiac Z‐disk stabilization and endothelial integrity in zebrafish
Talin (tln) binds and activates integrins to couple extracellular matrix‐bound integrins to the cytoskeleton; however, its role in heart development is not well characterized. We identified theExpand
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Sea ice drift tracking in the Bohai Sea using geostationary ocean color imagery
Abstract The Bohai Sea is located in the middle latitude region, which is an important economic development zone in China. However, sea ice drift causes significant economic losses in the winter. SeaExpand
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Lateral flow nucleic acid biosensor for Cu2+ detection in aqueous solution with high sensitivity and selectivity.
  • Zhiyuan Fang, Jing Huang, +6 authors L. Zeng
  • Chemistry, Medicine
  • Chemical communications
  • 23 November 2010
A lateral flow nucleic acid biosensor based on copper-dependent DNA-cleaving DNAzyme and gold nanoparticles has been developed for the visual detection of copper ions (Cu(2+)) in an aqueous solutionExpand
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Postnatal cerebellar defects in mice deficient in methylenetetrahydrofolate reductase
Patients with severe deficiency of methylenetetrahydrofolate reductase (MTHFR) suffer from a wide variety of neurological problems, which can begin in the neonatal period. MTHFR is a critical enzymeExpand
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