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- Publications
- Influence
The Hepatitis B Virus X Protein Disrupts Innate Immunity by Downregulating Mitochondrial Antiviral Signaling Protein
- Congwen Wei, C. Ni, +15 authors H. Zhong
- Biology, Medicine
- The Journal of Immunology
- 16 June 2010
Previous studies have shown that both hepatitis A virus and hepatitis C virus inhibit innate immunity by cleaving the mitochondrial antiviral signaling (MAVS) protein, an essential component of the… Expand
Gut microbiota and intestinal FXR mediate the clinical benefits of metformin
- L. Sun, Cen Xie, +25 authors Changtao Jiang
- Medicine
- Nature Medicine
- 5 November 2018
The anti-hyperglycemic effect of metformin is believed to be caused by its direct action on signaling processes in hepatocytes, leading to lower hepatic gluconeogenesis. Recently, metformin was… Expand
Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters
- L. Sun, Y. Pang, +7 authors Changtao Jiang
- Chemistry, Medicine
- Acta pharmaceutica Sinica. B
- 16 February 2019
Since metabolic process differs between humans and mice, studies were performed in hamsters, which are generally considered to be a more appropriate animal model for studies of obesity-related… Expand
Essential oil from Zanthoxylum bungeanum Maxim. and its main components used as transdermal penetration enhancers: a comparative study
- Y. Lan, H. Li, +4 authors Q. Wu
- Chemistry, Medicine
- Journal of Zhejiang University SCIENCE B
- 1 November 2014
Our previous studies had confirmed that the essential oil from Zanthoxylum bungeanum Maxim. (Z. bungeanum oil) could effectively enhance the percutaneous permeation of drug molecules as a natural… Expand
Microbial mechanisms of using enhanced ecological floating beds for eutrophic water improvement.
- Q. Wu, Y. Hu, Shuqun Li, S. Peng, Hua-bing Zhao
- Biology, Medicine
- Bioresource technology
- 1 July 2016
Enhanced ecological floating beds were implemented to reduce nutrient quantity and improve the water quality of a eutrophic lake. The results showed that average removal efficiencies of CODCr, total… Expand
Development of an Enzyme-linked Immuno-Sorbent Assay (ELISA) Method for Carbofuran Residues
- J. Yang, H. Wang, +7 authors Zhenlin Xu
- Chemistry, Medicine
- Molecules
- 1 April 2008
The haptens 4-[[(2,3-dihydro-2,2-dimethyl-7-benzofuranyloxy)carbonyl]-amino]butanoic acid (BFNB) and 6-[((2,3-dihydro-2,2-dimethyl-7-benzofuranyloxy)-carbonylamino]hexanoic acid (BFNH) were… Expand
Talin1 is required for cardiac Z‐disk stabilization and endothelial integrity in zebrafish
- Q. Wu, J. Zhang, +6 authors Jing-Wei Xiong
- Biology, Medicine
- FASEB journal : official publication of the…
- 26 August 2015
Talin (tln) binds and activates integrins to couple extracellular matrix‐bound integrins to the cytoskeleton; however, its role in heart development is not well characterized. We identified the… Expand
Sea ice drift tracking in the Bohai Sea using geostationary ocean color imagery
- Wenhui Lang, Q. Wu, Xi Zhang, J. Meng, Ning Wang, Yajing Cao
- Geology, Engineering
- 2014
Abstract The Bohai Sea is located in the middle latitude region, which is an important economic development zone in China. However, sea ice drift causes significant economic losses in the winter. Sea… Expand
Lateral flow nucleic acid biosensor for Cu2+ detection in aqueous solution with high sensitivity and selectivity.
- Zhiyuan Fang, Jing Huang, +6 authors L. Zeng
- Chemistry, Medicine
- Chemical communications
- 23 November 2010
A lateral flow nucleic acid biosensor based on copper-dependent DNA-cleaving DNAzyme and gold nanoparticles has been developed for the visual detection of copper ions (Cu(2+)) in an aqueous solution… Expand
Postnatal cerebellar defects in mice deficient in methylenetetrahydrofolate reductase
- Z. Chen, B. Schwahn, Q. Wu, Xinying He, R. Rozen
- Biology, Medicine
- International Journal of Developmental…
- 1 August 2005
Patients with severe deficiency of methylenetetrahydrofolate reductase (MTHFR) suffer from a wide variety of neurological problems, which can begin in the neonatal period. MTHFR is a critical enzyme… Expand