• Publications
  • Influence
The Amiloride-Sensitive Epithelial Na+ Channel PPK28 Is Essential for Drosophila Gustatory Water Reception
Water sensation is a specific taste modality in the fruit fly. Water-induced hypoosmolarity activates specific gustatory receptor neurons; however, the molecular identity of the putative osmolarityExpand
  • 82
  • 10
  • PDF
Transmembrane channel-like (tmc) gene regulates Drosophila larval locomotion
Significance Locomotion requires peripheral sensory feedback from mechanosensitive proprioceptors. The molecular mechanisms underlying this proprioceptive locomotion control are largely unknown. HereExpand
  • 41
  • 7
Integrated metabolomic analysis of the nano-sized copper particle-induced hepatotoxicity and nephrotoxicity in rats: a rapid in vivo screening method for nanotoxicity.
Despite an increasing application of copper nanoparticles, there is a serious lack of information concerning their impact on human health and the environment. In this study, the biochemicalExpand
  • 188
  • 6
Parallel pathways convey olfactory information with opposite polarities in Drosophila
Significance Olfactory information is relayed from the antennal lobes (ALs) to higher regions via parallel pathways formed by different projection neurons (PNs) in insects. Here we haveExpand
  • 34
  • 5
  • PDF
Expression patterns of two putative odorant-binding proteins in the olfactory organs of Drosophila melanogaster have different implications for their functions
Abstract. The aqueous medium bathing the dendrites of olfactory neurons contains high concentrations of odorant-binding proteins (OBPs) whose role is still unclear. OBPs may facilitate interactionsExpand
  • 56
  • 4
Novel genes expressed in subsets of chemosensory sensilla on the front legs of male Drosophila melanogaster
Abstract. Detection of courtship-activating female pheromones by contact chemoreceptors on the front legs of male Drosophila melanogaster is thought to play an important role in triggering courtshipExpand
  • 50
  • 4
The role of PPK26 in Drosophila larval mechanical nociception.
In Drosophila larvae, the class IV dendritic arborization (da) neurons are polymodal nociceptors. Here, we show that ppk26 (CG8546) plays an important role in mechanical nociception in class IV daExpand
  • 58
  • 4
  • PDF
Silencing of miRNA-218 promotes migration and invasion of breast cancer via Slit2-Robo1 pathway.
MiRNAs play an important role in regulating tumor migration and invasion, and abnormal expression of miRNAs occurs in various kinds of human cancers. In this essay, it is reported that the level ofExpand
  • 37
  • 2
NOMPC is likely a key component of Drosophila mechanotransduction channels
Mechanotransduction is the basis of several sensory modalities, including touch, hearing, proprioception and gravity sensation. Despite its importance to sensory processing and behavior, theExpand
  • 27
  • 2
  • PDF
The miR-29b-Sirt1 axis regulates self-renewal of mouse embryonic stem cells in response to reactive oxygen species.
Endogenous reactive oxygen species (ROS) control is important for the maintenance of self-renewal of embryonic stem (ES) cells. Although miRNAs have been found to be critically involved in theExpand
  • 17
  • 2