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Neuroprotective effects of tanshinone IIA and/or tetramethylpyrazine in cerebral ischemic injury in vivo and in vitro
The present study compared the potential neuroprotective effects of tanshinone (Tan) IIA monotherapy, tetramethylpyrazine (TMP) monotherapy, and Tan IIA+TMP combination therapy in adult rat subjectedExpand
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Tanshinone IIA Protects Hippocampal Neuronal Cells from Reactive Oxygen Species Through Changes in Autophagy and Activation of Phosphatidylinositol 3-Kinase, Protein Kinas B, and Mechanistic Target
Background: Tanshinone IIA is a key active ingredient of danshen, which is derived from the dried root or rhizome of Salviae miltiorrhizae Bge. The tanshinone IIA has protective effects against theExpand
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Role of suture diameter and vessel insertion position in the establishment of the middle cerebral artery occlusion rat model
The aim of the present study was to explore the role of suture diameter and vessel insertion position in the preparation of the middle cerebral artery occlusion (MCAO) rat model. A total of 84Expand
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Decreasing serum 25‐hydroxyvitamin D levels and risk of early neurological deterioration in patients with ischemic stroke
Vitamin D deficiency has been linked to a higher risk of ischemic stroke. We therefore explored the relationship between serum 25‐hydroxyvitamin D [25(OH)D] levels and early neurologicalExpand
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Protective effect of tanshinone IIA on the brain and its therapeutic time window in rat models of cerebral ischemia-reperfusion
The aims of the present study were to investigate the protective effect of tanshinone IIA on the brain and its therapeutic time window in a rat model of cerebral ischemia-reperfusion. The rat modelExpand
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Serum beta2-microglobulin levels are highly associated with the risk of acute ischemic stroke
Inflammation is considered an important mechanism of cell death or survival after ischemic stroke. As an important marker of inflammation, the role of β2-microglobulin (β2M) in acute ischemic strokeExpand
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Clinical and Magnetic Resonance Imaging Features of Reversible Splenial Lesion Syndrome in Adults: A Small Case Series
Background: To study clinical and magnetic resonance imaging (MRI) features of reversible splenial lesion syndrome (RESLES) in adult patients. Methods: A retrospective analysis was performed usingExpand
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NLRP3 Is Involved in the Maintenance of Cerebral Pericytes
Pericytes play a central role in regulating the structure and function of capillaries in the brain. However, molecular mechanisms that drive pericyte proliferation and differentiation are unclear. InExpand
Serum β2-Microglobulin Is Closely Associated With the Recurrence Risk and 3-Month Outcome of Acute Ischemic Stroke
Background and Purpose: Inflammation plays a significant role in the pathogenesis of acute ischemic stroke (AIS). The role of β2-microglobulin (β2M) as a potential initiator of the inflammatoryExpand
Analysis of age of onset, pre-existing infections, and features of magnetic resonance imaging results in patients with acute myelitis.
  • Q. Tang, H. Xiao
  • Biology, Medicine
  • Genetics and molecular research : GMR
  • 17 June 2014
The clinical features and potential risk factors of acute myelitis (AM) were investigated. The medical records of patients with AM admitted to our department between January 2004 and December 2011Expand