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Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction.
Recent studies have revealed the role of microRNAs (miRNAs) in a variety of basic biological and pathological processes and the association of miRNA signatures with human diseases. Circulating miRNAs… Expand
A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis.
The general transcription factor P-TEFb stimulates RNA polymerase II elongation and cotranscriptional processing of pre-mRNA. Contributing to a functional equilibrium important for growth control, a… Expand
Changes of serum omentin-1 levels in normal subjects and in patients with impaired glucose regulation and with newly diagnosed and untreated type 2 diabetes.
AIMS To assay the levels of serum omentin-1 in subjects with different levels of glucose regulation and to analyze the relationship between serum omentin-1 levels and body mass index (BMI),… Expand
Selective enhancement filters for nodules, vessels, and airway walls in two- and three-dimensional CT scans.
We developed three selective enhancement filters for dot, line, and plane which can simultaneously enhance objects of a specific shape (for example, dot-like nodules) and suppress objects of other shapes ( for example, line-like vessels) in 2D and 3D medical images. Expand
Nox2 and Rac1 Regulate H2O2-Dependent Recruitment of TRAF6 to Endosomal Interleukin-1 Receptor Complexes
- Q. Li, M. Harraz, +7 authors J. Engelhardt
- Biology, Medicine
- Molecular and Cellular Biology
- 1 January 2006
ABSTRACT Reactive oxygen species (ROS) generated by NADPH oxidases (Nox) have been implicated in the regulation of signal transduction. However, the cellular mechanisms that link Nox activation with… Expand
ANALYSIS OF 82 CASES OF RETROPERITONEAL SCHWANNOMA
Background: The aim of the study was to improve the diagnosis and treatment of retroperitoneal schwannoma by analysing clinical manifestations and postoperative course of this rare disease.
Regulation of adiponectin and leptin secretion and expression by insulin through a PI3K-PDE3B dependent mechanism in rat primary adipocytes.
Adiponectin is intimately involved in the regulation of insulin sensitivity, carbohydrate and lipid metabolism, and cardiovascular functions. The circulating concentration of adiponectin is decreased… Expand
Elevated expression of vascular endothelial growth factor correlates with increased angiogenesis and decreased progression‐free survival among patients with low‐grade neuroendocrine tumors
Vascular endothelial growth factor (VEGF) is a critical proangiogenic factor in solid tumors. However, its expression and role in human neuroendocrine tumor development and progression remains… Expand
Ser1369Ala Variant in Sulfonylurea Receptor Gene ABCC8 Is Associated With Antidiabetic Efficacy of Gliclazide in Chinese Type 2 Diabetic Patients
OBJECTIVE—The purpose of this study was to investigate whether genetic variants could influence the antidiabetic efficacy of gliclazide in type 2 diabetic patients. RESEARCH DESIGN AND METHODS—A… Expand
Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine.
- Q. Li, A. Manolescu, +5 authors Chris I. Cheeseman
- Biology, Medicine
- American journal of physiology. Gastrointestinal…
- 1 July 2004
Facilitated glucose transporters (GLUTs) mediate transport of sugars across cell membranes by using the chemical gradient of sugars as the driving force. Improved cloning techniques and database… Expand