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Structure of a kinesin–tubulin complex and implications for kinesin motility
The typical function of kinesins is to transport cargo along microtubules. Binding of ATP to microtubule-attached motile kinesins leads to cargo displacement. To better understand the nature of theExpand
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The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement.
Kinesin-1 is a dimeric ATP-dependent motor protein that moves towards microtubules (+) ends. This movement is driven by two conformations (docked and undocked) of the two motor domainsExpand
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A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end
Microtubules are cytoskeleton filaments consisting of αβ-tubulin heterodimers. They switch between phases of growth and shrinkage. The underlying mechanism of this property, called dynamicExpand
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Kif2C Minimal Functional Domain Has Unusual Nucleotide Binding Properties That Are Adapted to Microtubule Depolymerization*
Background: Kinesin-13 proteins, such as Kif2C, share a conserved motor domain with motile kinesins, but they depolymerize microtubules. Results: Kif2C is mostly ATP-bound, and Kif2C-ATP has a strongExpand
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Printed soft optical waveguides of PLA copolymers for guiding light into tissue.
The application of optical technologies in treating pathologies and monitoring disease states requires the development of soft, minimal invasive and implantable devices to deliver light to tissuesExpand
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4D hydrogel for dynamic cell culture with orthogonal, wavelength-dependent mechanical and biochemical cues
Cooperative action of biochemical and biomechanical signals regulates the interactions between cells and the supporting matrix in natural tissues. Herein, we describe a hydrogel for 4D cell cultureExpand
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Cryo-microscopie électronique des complexes de l'adressage et de la translocation co-traductionnelle chez E. coli
La membrane cellulaire est la barriere qui separe l'interieur des cellules de l'environnement exterieur. Elle se compose de lipides et de proteines. Les genes codant pour les proteines membranairesExpand
Near-infrared-light regulated angiogenesis in a 4D hydrogel.
Light-responsive hydrogels are useful platforms to study cellular responses. Current photosensitive motifs need UV light to be activated, which is intrinsically cytotoxic and has a low penetrationExpand
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