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BACKGROUND TGFβ1 and Smad3 play an important role in the process of EMT. TGFβ1 regulates the expression of Jagged1 by modulating Notch signaling. Jagged1 is related to tumor invasion, metastasis,… Continue Reading
Non-syndromic cleft of the lip and/or palate is one of the most common birth defects in humans. Embryonic palatal mesenchymal (EPM) cells are an attractive source for investigating embryonic palatal… Continue Reading
A two-stage cancer model was recently used to analyze some cancer incidence data for atomic bomb survivors by Kai, Luebeck and Moolgavkar (ref. 1). It is interesting to see that, unlike some… Continue Reading