Q M Luo

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The utility and performance of optical studies of tissue depends upon the contrast and the changes of contrast in health and disease and in functional activity. The contrast is determined both by the optical properties of extrinsic chromophores and scatterers but especially upon the changes evoked by physiological activity and pathological states. Here, we(More)
Continuous Wave Spectroscopy (CWS) has been used in human subjects to detect brain function by observation of brain oxygenation and blood volume changes. In this research, we have developed a device for imaging brain oxygenation and blood volume with multiple sources and detectors in an area of 10 x 12 cm. Twelve, 1 watt tungsten bulbs were used as a light(More)
Chuck had the acute foresightedness in taking the leadership to foster, support and actively encourage the international collaboration among us resulting in a much better understanding of the physics of propagation of intense femtosecond laser pulses in all optical media. In particular, our collective effort shows that national boundaries disappear when it(More)
All matters in the path of filaments induced by an intense femtosecond laser pulse propagating in air could be fragmented and result in the emission of characteristic fluorescence spectra from the excited fragments. The fluorescence spectra exhibit specific signatures (fingerprints) that can be used for the identification of various substances including(More)
OBJECTIVE To investigate the left prefrontal lobe activation during semantic and non-semantic encoding tasks with functional near-infrared imaging (fNIRI) technique. METHOD 22 healthy subjects were assigned semantic encoding and non-semantic encoding tasks. During semantic encoding tasks, subjects were asked to make a meaningful sentence including two(More)
Highly accurate sample drift correction is essential in super-resolution localization microscopy to guarantee a high spatial resolution, especially when the technique is used to visualize small cell organelle. Here we present a localization events-based drift correction method using a redundant cross-correlation algorithm originally developed to correct(More)
Localization-based super-resolution microscopy (or called localization microscopy) rely on repeated imaging and localization of active molecules, and the spatial resolution enhancement of localization microscopy is built upon the sacrifice of its temporal resolution. Developing algorithms for high-density localization of active molecules is a promising(More)
Laser speckle imaging (LSI) based on the speckle contrast analysis is a simple and robust technique for imaging of heterogeneous dynamics. LSI finds frequent application for dynamical mapping of cerebral blood flow, as it features high spatial and temporal resolution. However, the quantitative interpretation of the acquired data is not straightforward for(More)
Powerful femtosecond laser pulses propagate in an apparent form of filaments in all transparent optical media. This universal nonlinear phenomenon is currently an interesting topic of research at the forefront of applied physics with a lot of challenging physics and potential applications. Fundamentally, the physics of filamentation is based upon Kerr(More)
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