Learn More
Recently Simmons et al. reported a new mechanism for SARS virus entry into target cells, where MDL28170 was identified as an efficient inhibitor of CTSL-meditated substrate cleavage with IC50 of 2.5 nmol/l. Based on the molecule fingerprint searching method, 11 natural molecules were found in the Traditional Chinese Medicines Database (TCMD). Molecular(More)
We propose a time-sharing based rate adaptation scheme for reliable multicasting over the fading channels in mobile wireless networks. Specifically, the proposed scheme aims at achieving high system throughput/spectral-efficiency by dynamically adjusting the transmission rate according to the variations of channel state information (CSI) of all multicast(More)
Starting from a collection of 1386 druggable compounds obtained from the 3D pharmacophore search, we performed a similarity search to narrow down the scope of docking studies. The template molecule is KZ7088 (Chou et al., 2003, Biochem Biophys Res Commun 308: 148–151). The MDL MACCS keys were used to fingerprint the molecules. The Tanimoto coefficient is(More)
  • 1