Q D Han

Learn More
Interferon regulatory factor-4 binding protein (IBP) is a novel upstream activator of Rho GTPases. Our previous studies have shown that ectopic expression of IBP was correlated with malignant behaviors of human breast cancer cells, and invasive human breast cancer had high expression of IBP that promoted the proliferation of these cells. However, it remains(More)
The effect of RCMF-magnetic therapy apparatus on signal substances was studied. The radioimmunoassay (RIA) suggested that the magnetic field increased beta-endorphin markedly in plasma. ELISA indicated that the magnetic field inhibited vomiting reaction induced by chemotherapy drug, with reversible decrease of serotonin (5-HT) level in brains, small(More)
To investigate the changes of both CGRP release and synthesis during endotoxicosis, CGRP mRNA in thoracolumbar dorsal root ganglia (DRG) was determined by the semi-quantity RT-PCR and the CGRP levels in plasma were measured by RIA. The results showed that plasma CGRP, but not mRNA, began to increase 30 min after endotoxin (5 mg/kg, i.v.) administration. On(More)
In the present study, the role of calcium in endotoxin-induced CGRP release was studied. 2.5-50 microg/mL endotoxin and 1-10 mmol/L caffeine caused concentration-dependent increase of CGRP release from rat spinal cord in vitro. However, no additive effect could be found when caffeine and endotoxin were concomitantly incubated. By using capsaicin,(More)
Electrical stimulation of the left stellate ganglion in guinea pig heart evoked a calcium-dependent, exocytotic release of neuropeptide Y (NPY). Stimulation after 10 min of global ischemia (S2), compared with control period stimulation (S1), had no significant effect on the NPY release. The release of NPY produced by the same stimulation after 20 min of(More)
The Ca2+ influx is mainly mediated by voltage-dependent Ca2+ channels and store depletion-dependent Ca2+ channels. The former, which mainly acts to regulate Ca2+ influx in excitable cells, is relatively clear; However, the later, which mainly functions in nonexcitable cells, remains enigmatically complicated. Following activation of the intracellular Ca2+(More)
  • 1