Pyo-Jong Lee

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OBJECTIVE To determine the ability of interleukin-4 (IL-4) to inhibit the degradation of proteoglycan in bovine articular cartilage explants stimulated by human interleukin-1 (IL-1 alpha), tumor necrosis factor (TNF-alpha), a combination of TNF-alpha and IL-1 alpha, and lipopolysaccharide (LPS). METHODS 35SO4 radiolabelled bovine radiocarpal cartilage(More)
The aim of this study was to establish a multi-center birth defects monitoring system to evaluate the prevalence and the serial occurrence of birth defects in Korea. Ten medical centers participated in this program. A trained nurse collected relevant records from delivery units and pediatric clinics in participating hospitals on a monthly basis. We observed(More)
Nonsteroidal antiinflammatory drugs are widely used for increasingly broad indications. This article reviews the major issues encountered in the clinic in choosing and prescribing a specific agent to a given individual. A parallel view of the information available that would enable such decisions to be made logically reveals major gaps in the available(More)
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