Pushpendra Singh

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Insulin and insulin-like growth factor (IGF) signaling system, commonly known for fine-tuning numerous biological processes, has lately made its mark as a much sought-after therapeutic targets for diabetes and cancer. These receptors make an attractive anticancer target owing to their overexpression in variety of cancer especially in prostate and breast(More)
The role played by overexpression of tyrosine kinase epidermal growth factor receptor (EGFR), the transmembrane receptor central to numerous cellular processes comprising cell migration, adhesion, apoptosis, and cell proliferation, has been highlighted in various cancers such as prostate, breast, lung, and ovarian cancers as well as in mutations in the EGFR(More)
The archaic centralized software systems, currently used to manage buildings, make it hard to incorporate advances in sensing technology and user-level applications, and present hurdles for experimental validation of open research in building information technology. Motivated by this, we --- a transnational collaboration of researchers engaged in(More)
Mobile phones have emerged as truly pervasive and affordable Information and Communication Technology (ICT) platform in the last decade. Large penetration of cellular networks and availability of advanced hardware platforms have inspired multiple innovative research opportunities in mobile computing domain. However, most of the research challenges have(More)
Social programs often require collection of demographic and program related information. Pen-paper surveys have been the most favorable way of collecting such information. However, with proliferation of smartphones, low cost mobile connectivity with good coverage and availability of several data collection applications that can even work around the(More)
Receptors for growth factors encompass within the superfamily of receptor tyrosine kinases and are known to regulate numerous biological processes including cellular growth, proliferation, metabolism, survival, cell differentiation and apoptosis. These receptors have recently caught the attention of the researchers as an attractive target to combat cancer(More)
Signal transducer and activator of transcription (STAT) family, encompassing protein molecules that function as a second messenger and transcription factor, are famously known to regulate a multitude of cellular processes including inflammation, cell proliferation, invasion, angiogenesis, metastasis and immune system homeostasis. STAT3 is one of the six(More)